IC50 values for AGS-16C3F on different human neoplastic mast cell lines
| Human mast cell line . | IC50 values, nM . |
|---|---|
| ROSAKIT D816V | 1.10 ± 0.14 |
| ROSAKIT D816V-Gluc | 2.73 ± 0.77 |
| HMC-1.1 | 109.90 ± 1.15 |
| HMC-1.2 | 146.50 ± 37.65 |
| Human mast cell line . | IC50 values, nM . |
|---|---|
| ROSAKIT D816V | 1.10 ± 0.14 |
| ROSAKIT D816V-Gluc | 2.73 ± 0.77 |
| HMC-1.1 | 109.90 ± 1.15 |
| HMC-1.2 | 146.50 ± 37.65 |
Data presented as mean ± standard deviation. IC50 values were determined using the 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazoliumbromide method after 120 hours of treatment. IC50 values at day 5 for AGS-16C3F were calculated for each cell line, using Prism GraphPad 6.0 software, after plotting log concentration vs response.