Table 1. JAK2 V617F allele burden in... | American Society of Hematology

Table 1.

JAK2^V617F allele burden in TNF-α⁺ monocytes

Patient	4 h		10 h
Patient	TNF-α⁻	TNF-α⁺	TNF-α⁻	TNF-α⁺
192	92.21	57.52	85.58	82.65
228	63.66	57.92	90.01	78.10
232	34.88	42.66	53.13	51.90
252	94.84	90.50	66.20	63.45
255	20.95	76.86	75.24	80.23

Patient	4 h		10 h
Patient	TNF-α⁻	TNF-α⁺	TNF-α⁻	TNF-α⁺
192	92.21	57.52	85.58	82.65
228	63.66	57.92	90.01	78.10
232	34.88	42.66	53.13	51.90
252	94.84	90.50	66.20	63.45
255	20.95	76.86	75.24	80.23

MPN monocytes (n = 5) were stimulated with 10 ng/mL LPS for 4 or 10 hours in the presence of brefeldin A, and intracellularly stained for TNF-α. TNF-α⁺ cells were sorted and JAK2^V617F allele burden was determined by quantitative PCR.

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