Table 2. FVIII deficiency did not... | American Society of Hematology

Table 2.

FVIII deficiency did not improve the viability of Plg^−/−mice

Group	No. of mice in cohort	No. of mice euthanized/dead within 168 d (%)	Cause of death/euthanasia	Distribution of dead mice (%)
WT	30	0 (0)	Not applicable	Not applicable
F8^−/−	43	4 (9)	Unknown	4 (100)
Plg^−/−	23	18 (78)	RP/wasting	17 (94)
Plg^−/−	23	18 (78)	Unknown	1 (6)
F8^−/−/Plg^−/−	26	22 (85)	RP/wasting	20 (91)
F8^−/−/Plg^−/−	26	22 (85)	Unknown	2 (9)

Group	No. of mice in cohort	No. of mice euthanized/dead within 168 d (%)	Cause of death/euthanasia	Distribution of dead mice (%)
WT	30	0 (0)	Not applicable	Not applicable
F8^−/−	43	4 (9)	Unknown	4 (100)
Plg^−/−	23	18 (78)	RP/wasting	17 (94)
Plg^−/−	23	18 (78)	Unknown	1 (6)
F8^−/−/Plg^−/−	26	22 (85)	RP/wasting	20 (91)
F8^−/−/Plg^−/−	26	22 (85)	Unknown	2 (9)

Gross examination was used to determine cause of euthanasia/death.

RP, rectal prolapse.