Table 2.

Categories of patients and controls based on the presence or absence of leg ulcer

HbAA (Gp 1)SNLU (Gp 2)SWLU (Gp 3)P (Gp 1 vs 2 vs 3)P (Gp 1 vs 2)P (Gp 1 vs 3)P (Gp 2 vs 3)
n (limbs) 66 64 24     
BMI, median, kg/m2 21.64 18.08 19.84 <.001* <.001† .002† .298† 
Hb conc., median, g/dL ND 8.33 7.67 NA NA NA .003† 
WBCs, median, ×109/L ND 9.20 9.80 NA NA NA .136† 
Platelets, median, ×109/L ND 285.50 305.00 NA NA NA .851† 
O2 saturation, median, % 98.00 95.50 93.00 <.001* <.001† <.001† .033† 
sP-selectin, median, ng/mL 72.70 78.15 79.40 .001* .001† .003† .399† 
HbF, median, ng/mL 273.90 369.90 397.25 <.001* <.001† <.001† .626† 
HCY, median, μmol/L 8.30 13.85 13.72 <.001* <.001† <.001† .154† 
KIM1, median, pg/mL 125.00 445.00 460.00 <.001* <.001† <.001† .771† 
CysC, median, mg/L 1.10 4.50 5.70 <.001* <.001† <.001† .047† 
Creatinine, median, μmol/L ND 80.0 90.5 NA NA NA .368† 
CFA IMT, median, mm 0.60 0.70 1.0 <.001* <.001† <.001† <.001† 
HbAA (Gp 1)SNLU (Gp 2)SWLU (Gp 3)P (Gp 1 vs 2 vs 3)P (Gp 1 vs 2)P (Gp 1 vs 3)P (Gp 2 vs 3)
n (limbs) 66 64 24     
BMI, median, kg/m2 21.64 18.08 19.84 <.001* <.001† .002† .298† 
Hb conc., median, g/dL ND 8.33 7.67 NA NA NA .003† 
WBCs, median, ×109/L ND 9.20 9.80 NA NA NA .136† 
Platelets, median, ×109/L ND 285.50 305.00 NA NA NA .851† 
O2 saturation, median, % 98.00 95.50 93.00 <.001* <.001† <.001† .033† 
sP-selectin, median, ng/mL 72.70 78.15 79.40 .001* .001† .003† .399† 
HbF, median, ng/mL 273.90 369.90 397.25 <.001* <.001† <.001† .626† 
HCY, median, μmol/L 8.30 13.85 13.72 <.001* <.001† <.001† .154† 
KIM1, median, pg/mL 125.00 445.00 460.00 <.001* <.001† <.001† .771† 
CysC, median, mg/L 1.10 4.50 5.70 <.001* <.001† <.001† .047† 
Creatinine, median, μmol/L ND 80.0 90.5 NA NA NA .368† 
CFA IMT, median, mm 0.60 0.70 1.0 <.001* <.001† <.001† <.001† 

Gp, group; NA, not applicable; ND, not determined.

*

Kruskal-Wallis test applied.

†

Mann-Whitney U test applied.

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