Summary of rearrangement partners identified in the MYC region using capture sequencing
| . | Total breakpoints . | IGH partner . | IGK/IGL partner . | Non-IG partner . |
|---|---|---|---|---|
| Genic cluster | 35 | 28 (80) | 0 (0) | 7 (20) |
| Other | 70 | 7 (10) | 8 (11) | 55 (79) |
| Single-hit | 34 | 14 (41) | 3 (9) | 17 (50) |
| HGBL-DH | 69 | 19 (28) | 5 (7) | 45 (65) |
| GCB | 71 | 19 (27) | 6 (8) | 46 (65) |
| ABC/non-GCB | 25 | 11 (44) | 2 (8) | 12 (48) |
| . | Total breakpoints . | IGH partner . | IGK/IGL partner . | Non-IG partner . |
|---|---|---|---|---|
| Genic cluster | 35 | 28 (80) | 0 (0) | 7 (20) |
| Other | 70 | 7 (10) | 8 (11) | 55 (79) |
| Single-hit | 34 | 14 (41) | 3 (9) | 17 (50) |
| HGBL-DH | 69 | 19 (28) | 5 (7) | 45 (65) |
| GCB | 71 | 19 (27) | 6 (8) | 46 (65) |
| ABC/non-GCB | 25 | 11 (44) | 2 (8) | 12 (48) |
Total counts of rearrangements are shown with percentages in parentheses. Counts include translocations and large intrachromosomal rearrangements (>2 Mb). Rearrangements that failed validation and low-confidence predictions in nonvalidated cases have been omitted.
ABC, activated B-cell–like DLBCL.