Table 1.

vWf production by rhIL-11–treated HUVECs

IL-11 (ng/mL)vWf (mU/mL)
Incubation times
3 hours72 hours
2.8 4.7 ± 0.22 
10 2.6 4.4 ± 0.45  
1000 2.7 4.0 ± 0.11 
IL-11 (ng/mL)vWf (mU/mL)
Incubation times
3 hours72 hours
2.8 4.7 ± 0.22 
10 2.6 4.4 ± 0.45  
1000 2.7 4.0 ± 0.11 

HUVECs were grown in the presence of 20% serum and treated with rhIL-11 or placebo for 3 hours or 72 hours. We measured vWf concentration in the culture supernatant of the treated cells using an ELISA technique as described in “Materials and methods.” Data from a representative experiment are shown for the 3-hour incubation, whereas the 72-hour incubation was performed in triplicate.

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