Table 2. Expression of immunoglobulin,... | American Society of Hematology

Table 2.

Expression of immunoglobulin, Oct1, Oct2, and BOB.1/OBF.1 in classical Hodgkin disease–derived cell lines and B-cell lines

Transcripts and proteins	L428	KM-H2	B-cell lines^*
Immunoglobulin mRNA^†	−	−	+
Immunoglobulin protein^‡	−	−	+
Oct1 mRNA^†,^2-153	+	+	+
Oct1 protein^‡	+	+	+
Oct2 mRNA^†,^2-153	−	−	+
Oct2 protein^‡,^2-154	−	−	+
BOB.1 mRNA^†,^2-153	−	−	+
BOB.1 protein^2-154	−	−	+

Transcripts and proteins	L428	KM-H2	B-cell lines^*
Immunoglobulin mRNA^†	−	−	+
Immunoglobulin protein^‡	−	−	+
Oct1 mRNA^†,^2-153	+	+	+
Oct1 protein^‡	+	+	+
Oct2 mRNA^†,^2-153	−	−	+
Oct2 protein^‡,^2-154	−	−	+
BOB.1 mRNA^†,^2-153	−	−	+
BOB.1 protein^2-154	−	−	+

mRNA indicates messenger RNA.

B-JAB, Namalwa, Raji, Jok-1, and DG-75.

Northern blot analysis.

Immunocytology.

Reverse transcriptase-polymerase chain reaction.

Western blot analysis.