Blood parameters insphDem/sphDem and normal mice
| Genotype (No. of mice) . | RBC count (×1012/L) . | Hematocrit (%) . | Hemoglobin (g/dL) . | MCV (μm3) . | MCHC (g/dL) . | Reticulocyte (%) . |
|---|---|---|---|---|---|---|
| +/+ (7) | 11.24 ± 0.43 | 52.9 ± 1.9 | 14.4 ± 0.6 | 47.3 ± 1.9 | 27.1 ± 0.4 | 2 |
| sphDem/sphDem (15) | 5.36 ± 0.27 | 30.1 ± 1.3 | 5.5 ± 0.3 | 56.9 ± 2.0 | 18.4 ± 0.5 | 50 |
| Genotype (No. of mice) . | RBC count (×1012/L) . | Hematocrit (%) . | Hemoglobin (g/dL) . | MCV (μm3) . | MCHC (g/dL) . | Reticulocyte (%) . |
|---|---|---|---|---|---|---|
| +/+ (7) | 11.24 ± 0.43 | 52.9 ± 1.9 | 14.4 ± 0.6 | 47.3 ± 1.9 | 27.1 ± 0.4 | 2 |
| sphDem/sphDem (15) | 5.36 ± 0.27 | 30.1 ± 1.3 | 5.5 ± 0.3 | 56.9 ± 2.0 | 18.4 ± 0.5 | 50 |
All values except reticulocyte percentages are mean ± SEM; all mutant values are significantly different (P ≤ .005). RBC = red blood cell; MCV = mean cell volume; MCHC = mean corpuscular hemoglobin concentration.