Plasma levels of autoantibodies against OxCL, MDA-LDL, and Ox-LDL in untreated apoE−/− mice on chow at 8 weeks and 26 weeks of age
| Autoantibodies (RLU/100 ms) . | Age 8 wk . | Age 26 wk . | P value . |
|---|---|---|---|
| IgG (OxCL) | 987 ± 222 | 10 662 ± 3144 | < .01 |
| IgM (OxCL) | 2120 ± 327 | 36 894 ± 8018 | <. 001 |
| IgG (MDA-LDL) | 7210 ± 620 | 19 414 ± 2043 | < .001 |
| IgM (MDA-LDL) | 22 059 ± 1585 | 47 637 ± 3414 | < .001 |
| IgG (Ox-LDL) | 1850 ± 249 | 4181 ± 466 | < .05 |
| IgM (Ox-LDL) | 4552 ± 434 | 10 313 ± 1470 | < .01 |
| Autoantibodies (RLU/100 ms) . | Age 8 wk . | Age 26 wk . | P value . |
|---|---|---|---|
| IgG (OxCL) | 987 ± 222 | 10 662 ± 3144 | < .01 |
| IgM (OxCL) | 2120 ± 327 | 36 894 ± 8018 | <. 001 |
| IgG (MDA-LDL) | 7210 ± 620 | 19 414 ± 2043 | < .001 |
| IgM (MDA-LDL) | 22 059 ± 1585 | 47 637 ± 3414 | < .001 |
| IgG (Ox-LDL) | 1850 ± 249 | 4181 ± 466 | < .05 |
| IgM (Ox-LDL) | 4552 ± 434 | 10 313 ± 1470 | < .01 |
Results are expressed as mean ± standard error of the mean, n = 10 for each age group.
OxCL indicates oxidized cardiolipin; MDA-LDL, malondialdehyde-modified low-density lipoprotein; Ox-LDL, oxidized low-density lipoprotein.