Table 2.

Myeloma isotypes and switch regions involved in illegitimate recombinations

Tumor isotypeSwitch region(s) involved in illegitimate recombinations
Sμ, SγSμ, SαSμ, Sα, Sγ
IgGκ  
IgAκ   
IgMλ     
κ     
Tumor isotypeSwitch region(s) involved in illegitimate recombinations
Sμ, SγSμ, SαSμ, Sα, Sγ
IgGκ  
IgAκ   
IgMλ     
κ     

The figures denote the number of cases in each category. All patients except one (IgGκ; illegitimate switches in Sμ, Sγ) were in progressive phase.

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