Subjective response indicates as self-reported by the patient. IV antibiotic therapy includes any hospital admission for IV antibiotic therapy for proven or suspected infection within the 12 months prior to initiation of any cytokine therapy. Pretherapy indicates the 12-month period before the start of any cytokine therapy; on therapy, the 3-year study period. OCR indicates objective clinical response (no hospitalization for IV antibiotics during the study), and NCR indicates no clinical response (at least one hospitalization for IV antibiotics occurred during the study). N/A = not applicable.