Toxicities grade 3 or above, according to MedRA category coding occurring at least once during maintenance therapy
| . | All patients (n = 97), n (%) . | After alloHCT (n = 75), n (%) . | After HiDAC (n = 22), n (%) . | P . |
|---|---|---|---|---|
| Gastrointestinal | 68 (70) | 60 (80) | 8 (36) | .0001 |
| Infection | 49 (51) | 42 (56) | 7 (32) | .06 |
| Febrile neutropenia | 14 (14) | 10 (13) | 4 (18) | .73 |
| Blood/marrow | 46 (47) | 39 (52) | 1 (5) | <.0001 |
| Pain | 37 (38) | 34 (45) | 3 (14) | <.0001 |
| Constitutional | 35 (36) | 29 (39) | 6 (27) | .45 |
| Allergy/immunology | 33 (34) | 32 (43) | 1 (5) | .006 |
| Metabolic/laboratory | 37 (38) | 35 (47) | 2 (9) | .15 |
| Dermatological | 29 (30) | 27 (36) | 2 (9) | .02 |
| Neurologic | 24 (25) | 20 (27) | 4 (18) | .58 |
| Renal/genitourinary | 23 (24) | 23 (31) | .001 | |
| Pulmonary/upper respiratory | 16 (16) | 15 (20) | 1 (5) | .11 |
| Musculoskeletal/soft tissue | 13 (13) | 11 (15) | 2 (9) | .73 |
| Ocular/visual | 13 (13) | 12 (16) | 1 (5) | .29 |
| Cardiac general | 13 (13) | 11 (15) | 2 (9) | .72 |
| Hemorrhage/bleeding | 7 (7) | 7 (9) | .34 | |
| Auditory/ear | 7 (7) | 7 (9) | .34 | |
| Cardiac arrhythmia | 5 (5) | 2 (3) | 3 (14) | .07 |
| Hepatobiliary/pancreas | 4 (4) | 4 (5) | .57 | |
| Secondary malignancy | 2 (2) | 2 (3) | .99 | |
| Other | 18 (19) | 16 (21) | 2 (9) | .35 |
| . | All patients (n = 97), n (%) . | After alloHCT (n = 75), n (%) . | After HiDAC (n = 22), n (%) . | P . |
|---|---|---|---|---|
| Gastrointestinal | 68 (70) | 60 (80) | 8 (36) | .0001 |
| Infection | 49 (51) | 42 (56) | 7 (32) | .06 |
| Febrile neutropenia | 14 (14) | 10 (13) | 4 (18) | .73 |
| Blood/marrow | 46 (47) | 39 (52) | 1 (5) | <.0001 |
| Pain | 37 (38) | 34 (45) | 3 (14) | <.0001 |
| Constitutional | 35 (36) | 29 (39) | 6 (27) | .45 |
| Allergy/immunology | 33 (34) | 32 (43) | 1 (5) | .006 |
| Metabolic/laboratory | 37 (38) | 35 (47) | 2 (9) | .15 |
| Dermatological | 29 (30) | 27 (36) | 2 (9) | .02 |
| Neurologic | 24 (25) | 20 (27) | 4 (18) | .58 |
| Renal/genitourinary | 23 (24) | 23 (31) | .001 | |
| Pulmonary/upper respiratory | 16 (16) | 15 (20) | 1 (5) | .11 |
| Musculoskeletal/soft tissue | 13 (13) | 11 (15) | 2 (9) | .73 |
| Ocular/visual | 13 (13) | 12 (16) | 1 (5) | .29 |
| Cardiac general | 13 (13) | 11 (15) | 2 (9) | .72 |
| Hemorrhage/bleeding | 7 (7) | 7 (9) | .34 | |
| Auditory/ear | 7 (7) | 7 (9) | .34 | |
| Cardiac arrhythmia | 5 (5) | 2 (3) | 3 (14) | .07 |
| Hepatobiliary/pancreas | 4 (4) | 4 (5) | .57 | |
| Secondary malignancy | 2 (2) | 2 (3) | .99 | |
| Other | 18 (19) | 16 (21) | 2 (9) | .35 |