Table 3.

Time receiving maintenance therapy, and reasons for early termination

All patients (n = 97)alloHCT (n = 75)HiDAC (n = 22)P
Months, median (range) 9 (1-13) 9 (1-13) 10.5 (1-12) .82 
Early termination, n (%)     
 Total 60 (61.8) 44 (58.7) 16 (72.7) .32 
  Death 1 (1.7) 1 (2.3) .99 
  IC/patients’ wish 11 (18.3) 11 (25) .06 
  Midostaurin toxicity 28 (46.6) 24 (54.55) 4 (25) .29 
  Other reasons* 7 (11.7) 2 (4.55)* 5 (31.25) .006 
  Relapse 13 (21.7) 6 (13.6) 7 (43.75) .009 
All patients (n = 97)alloHCT (n = 75)HiDAC (n = 22)P
Months, median (range) 9 (1-13) 9 (1-13) 10.5 (1-12) .82 
Early termination, n (%)     
 Total 60 (61.8) 44 (58.7) 16 (72.7) .32 
  Death 1 (1.7) 1 (2.3) .99 
  IC/patients’ wish 11 (18.3) 11 (25) .06 
  Midostaurin toxicity 28 (46.6) 24 (54.55) 4 (25) .29 
  Other reasons* 7 (11.7) 2 (4.55)* 5 (31.25) .006 
  Relapse 13 (21.7) 6 (13.6) 7 (43.75) .009 

IC, withdrawal of informed consent.

*

Thrombocytopenia, lung cancer.

Molecular relapse, myelodysplastic syndrome, accidental mistake in midostaurin intake (n = 2), lost to follow-up.

Close Modal

or Create an Account

Close Modal
Close Modal