Table 4.

Clinical factors and association with CVC-related thrombosis

FactorsAdmissionFollow-up
nχ2*OR (95%CI)nχ2*OR (95%CI)
PP
ECMO       
 Yes 14 0.6 1.4 (0.41-4.8) 0.29 2.46 (0.45-13.5) 
 No 126 P = 0.6 109 P = .3 
Open chest       
 Yes 14 0.23 2.0 (0.62-6.5) 0.2 2.98 (0.52-16.98) 
 No 125 P = .2 110 P = .2 
Cardiac arrest       
 Yes 23 0.01 3.32 (1.29-8.55) 14 0.06 3.35 (0.89-12.49) 
 No 117 P = .01 103 P = .07 
Age       
 <1 y 79 0.8 0.89 (0.4-1.97) 54 0.24 1.9 (0.64-6.04) 
 >1 y 67 P = .7 66 P = .2 
UFH       
 ≤10 units 104 0.03 2.05 (0.63-6.7) 86 0.45 0.93 (0.1-8.2) 
 >10 units 16 P = .2 10 P = .9 
Hypotension       
 Yes 47 0.11 1.9 (0.85-4.28) 35 0.05 2.85 (0.98-8.34) 
 No 99 P = .1 85 P = .05 
Bleeding       
 Yes 11 0.05 3.3 (0.93-11.67) 0.3 2.3 (0.43-12.7) 
 No 135 P = .06 112 P = .3 
FactorsAdmissionFollow-up
nχ2*OR (95%CI)nχ2*OR (95%CI)
PP
ECMO       
 Yes 14 0.6 1.4 (0.41-4.8) 0.29 2.46 (0.45-13.5) 
 No 126 P = 0.6 109 P = .3 
Open chest       
 Yes 14 0.23 2.0 (0.62-6.5) 0.2 2.98 (0.52-16.98) 
 No 125 P = .2 110 P = .2 
Cardiac arrest       
 Yes 23 0.01 3.32 (1.29-8.55) 14 0.06 3.35 (0.89-12.49) 
 No 117 P = .01 103 P = .07 
Age       
 <1 y 79 0.8 0.89 (0.4-1.97) 54 0.24 1.9 (0.64-6.04) 
 >1 y 67 P = .7 66 P = .2 
UFH       
 ≤10 units 104 0.03 2.05 (0.63-6.7) 86 0.45 0.93 (0.1-8.2) 
 >10 units 16 P = .2 10 P = .9 
Hypotension       
 Yes 47 0.11 1.9 (0.85-4.28) 35 0.05 2.85 (0.98-8.34) 
 No 99 P = .1 85 P = .05 
Bleeding       
 Yes 11 0.05 3.3 (0.93-11.67) 0.3 2.3 (0.43-12.7) 
 No 135 P = .06 112 P = .3 

ECMO, extracorporeal membrane oxygenation; NB, not all patients received unfractionated heparin.

*

Two sided.

Major bleeding and clinically relevant bleeding.

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