Table 2.

Cohort demographics

Number of patientsIncidence, %
Eligible consented patients   
 Age of patients at CVC insertion, median (range), y 1 (0-17)  
 Male sex 98 51.9 
 Weight, median (range), kg 8.7 (2.2-90)  
Primary diagnosis  
 Cyanotic CHD 42 22.2 
 Acyanotic CHD 100 52.9 
 Other cardiac 34.2 
 Respiratory 4.8 
 Sepsis/viral illness 4.2 
 Neurology/neurosurgery 4.2 
 Orthopedic surgery 3.2 
 Motor vehicle accident 1.6 
 Renal failure 1.6 
 Burns 0.55 
 Liver transplant 0.55 
CVC characteristics   
 Time in situ, median (range), d 4 (1-36)  
 Jugular 154 81.5 
 Femoral 35 18.5 
Unit inserted, n (%)   
 Operating theater 144 (76.2)  
 PICU 42 (22.2)  
 Other* 3 (1.6)  
Parameter   
 Dose UFH thromboprophylaxis, mean (SD), units per kg/h 157 10.4 (3.8) 
 PIM2 score, median (range) 180 2.0 (0.14-100) 
 D-dimer, median (range) 184 0.71 (0.27-20) 
 Factor VIII, median (range) 56 178 (59-516) 
Number of patientsIncidence, %
Eligible consented patients   
 Age of patients at CVC insertion, median (range), y 1 (0-17)  
 Male sex 98 51.9 
 Weight, median (range), kg 8.7 (2.2-90)  
Primary diagnosis  
 Cyanotic CHD 42 22.2 
 Acyanotic CHD 100 52.9 
 Other cardiac 34.2 
 Respiratory 4.8 
 Sepsis/viral illness 4.2 
 Neurology/neurosurgery 4.2 
 Orthopedic surgery 3.2 
 Motor vehicle accident 1.6 
 Renal failure 1.6 
 Burns 0.55 
 Liver transplant 0.55 
CVC characteristics   
 Time in situ, median (range), d 4 (1-36)  
 Jugular 154 81.5 
 Femoral 35 18.5 
Unit inserted, n (%)   
 Operating theater 144 (76.2)  
 PICU 42 (22.2)  
 Other* 3 (1.6)  
Parameter   
 Dose UFH thromboprophylaxis, mean (SD), units per kg/h 157 10.4 (3.8) 
 PIM2 score, median (range) 180 2.0 (0.14-100) 
 D-dimer, median (range) 184 0.71 (0.27-20) 
 Factor VIII, median (range) 56 178 (59-516) 

From total sample of n = 189.

SD, standard deviation; UFH, unfractionated heparin.

*

Angiography suite, Pediatric Emergency Transport Service, Emergency Department.

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