| Type patients for multiple antigens in a single assay |
| Type patients who have been recently transfused or RBCs coated with immunoglobulin |
| Type patients with autoimmune hemolytic anemia (to select antigen-negative RBCs for transfusion and adsorption of autoantibodies when searching for underlying alloantibodies) |
| Type patients receiving monoclonal antibody therapies that interfere with pretransfusion testing |
| Type RBCs when commercial antisera are not available |
| Type obstetric patients to identify weak D and partial D phenotypes to determine candidates for RhIg and to avoid use of limited RhD− blood) |
| Resolve blood group typing discrepancies |
| Determine paternal zygosity for RHD and HPA |
| Type fetus to determine risk for HDFN or FNAIT |
| Accurate Rh antigen matching in SCD |
| Type patients for multiple antigens in a single assay |
| Type patients who have been recently transfused or RBCs coated with immunoglobulin |
| Type patients with autoimmune hemolytic anemia (to select antigen-negative RBCs for transfusion and adsorption of autoantibodies when searching for underlying alloantibodies) |
| Type patients receiving monoclonal antibody therapies that interfere with pretransfusion testing |
| Type RBCs when commercial antisera are not available |
| Type obstetric patients to identify weak D and partial D phenotypes to determine candidates for RhIg and to avoid use of limited RhD− blood) |
| Resolve blood group typing discrepancies |
| Determine paternal zygosity for RHD and HPA |
| Type fetus to determine risk for HDFN or FNAIT |
| Accurate Rh antigen matching in SCD |
RhIg, Rh immune globulin.