Pretreatment characteristics of 331 t(8;21) AML patients (N = 331)
| Characteristics . | Data . |
|---|---|
| Age, median (range), y | 41.7 (15-84) |
| Sex, n (%) | |
| Male | 188 (57) |
| Female | 143 (43) |
| Diagnostic timeframe, n (%) | |
| 1990-1999 | 75 (23) |
| 2000-2004 | 76 (23) |
| 2005-2010 | 93 (28) |
| 2010-2016 | 87 (26) |
| Morphology, n (%) | |
| AML with minimal differentiation | 9 (3) |
| AML without maturation | 28 (9) |
| AML with maturation | 260 (84) |
| Acute myelomonocytic leukemia | 11 (3) |
| Acute monoblastic/monocytic leukemia | 3 (1) |
| Missing data | 20 |
| Type of AML, n (%) | |
| De novo | 305 (94) |
| Secondary | 10 (3) |
| Therapy related | 9 (3) |
| Missing data | 7 |
| Additional cytogenetic aberration, n | |
| Loss of X chromosome | 43 |
| Loss of Y chromosome | 108 |
| Trisomy 8 | 10 |
| −7/del7q | 11 |
| del9q | 37 |
| Others | 64 |
| Bone marrow blasts | |
| Mean, % | 56.8 |
| Missing data, n | 50 |
| WBC count | |
| Median, ×109/L | 17.9 |
| Range, ×109/L | 0.9-153 |
| Missing data, n | 10 |
| Hemoglobin | |
| Median, g/L | 8.1 |
| Range, g/L | 2.5-15.4 |
| Missing data, n | 60 |
| Platelet count | |
| Median, ×109/L | 51.5 |
| Range, ×109/L | 3-647 |
| Missing data, n | 40 |
| Characteristics . | Data . |
|---|---|
| Age, median (range), y | 41.7 (15-84) |
| Sex, n (%) | |
| Male | 188 (57) |
| Female | 143 (43) |
| Diagnostic timeframe, n (%) | |
| 1990-1999 | 75 (23) |
| 2000-2004 | 76 (23) |
| 2005-2010 | 93 (28) |
| 2010-2016 | 87 (26) |
| Morphology, n (%) | |
| AML with minimal differentiation | 9 (3) |
| AML without maturation | 28 (9) |
| AML with maturation | 260 (84) |
| Acute myelomonocytic leukemia | 11 (3) |
| Acute monoblastic/monocytic leukemia | 3 (1) |
| Missing data | 20 |
| Type of AML, n (%) | |
| De novo | 305 (94) |
| Secondary | 10 (3) |
| Therapy related | 9 (3) |
| Missing data | 7 |
| Additional cytogenetic aberration, n | |
| Loss of X chromosome | 43 |
| Loss of Y chromosome | 108 |
| Trisomy 8 | 10 |
| −7/del7q | 11 |
| del9q | 37 |
| Others | 64 |
| Bone marrow blasts | |
| Mean, % | 56.8 |
| Missing data, n | 50 |
| WBC count | |
| Median, ×109/L | 17.9 |
| Range, ×109/L | 0.9-153 |
| Missing data, n | 10 |
| Hemoglobin | |
| Median, g/L | 8.1 |
| Range, g/L | 2.5-15.4 |
| Missing data, n | 60 |
| Platelet count | |
| Median, ×109/L | 51.5 |
| Range, ×109/L | 3-647 |
| Missing data, n | 40 |
WBC, white blood cell.