Patient characteristics according to organ involvement at Dx
| Characteristic . | Total . | Skin only . | Systemic only without skin . | Skin and systemic . | Incomplete staging . | P* . |
|---|---|---|---|---|---|---|
| N | 59 | 11 | 10 | 28 | 10 | |
| Age at Dx, median (range), y | 66 (6, 91) | 66 (11, 78) | 61 (26, 84) | 63 (15, 84) | 77 (6, 91) | .98 |
| <60 | 12 (20) | 3 (27) | 4 (40) | 9 (32) | 1 (10) | .84 |
| ≥60 | 47 (80) | 8 (73) | 6 (60) | 19 (68) | 9 (90) | |
| Sex | ||||||
| Female | 12 (20) | 3 (27) | 2 (20) | 5 (18) | 2 (20) | .89 |
| Male | 47 (80) | 8 (73) | 8 (80) | 23 (82) | 8 (80) | |
| Ethnicity | ||||||
| White | 37 (63) | 6 (54) | 6 (60) | 22 (79) | 3 (30) | .20 |
| Other | 9 (15) | 4 (36) | 2 (20) | 3 (10) | 0 (0) | |
| Unknown | 13 (22) | 1 (9) | 2 (20) | 3 (11) | 7 (70) | |
| Karyotype† | ||||||
| Normal | 24 (65) | 9 (100) | 5 (50) | 10 (59) | 0 (0) | .036 |
| Abnormal | 13 (35) | 0 (0) | 5 (50) | 7 (41) | 1 (100) | — |
| Unknown | 22 | 2 | 0 | 11 | 9 | — |
| Other malignancy | ||||||
| Yes | 23 (39) | 3 (27) | 4 (40) | 15 (54) | 1 (10) | .17 |
| None | 15 (25) | 6 (55) | 2 (20) | 6 (21) | 1 (10) | |
| Unknown | 21 (36) | 2 (18) | 4 (40) | 7 (25) | 8 (80) | |
| WBC at Dx, median (range) | 5.3 (1.1, 170.0) | 5.4 (2.6, 10.0) | 5.5 (1.1, 170.0) | 5.2 (1.6, 10.0) | 3.1 | .85 |
| Platelet at Dx, median (range) | 129 (16, 399) | 149 (76, 279) | 90 (29, 399) | 128 (16, 280) | 214 | .41 |
| Hgb at Dx, median (range) | 12.3 (6.9, 16.3) | 13.3 (11.4, 16.3) | 9.7 (6.9, 14.2) | 11.9 (7.6, 16.0) | 13.1 | .019 |
| MCV at Dx, median (range) | 90 (73, 225) | 91.1 (82.0, 111.0) | 89.4 (75.0, 225.0) | 90.0 (73.0, 110.2) | 91.8 | .82 |
| No. of sites, median (range) | 2 (1, 4) | — | — | — | — | — |
| Site of involvement†,‡ | ||||||
| Skin | 39 (80) | 11 (100) | 0 (0) | 28 (100) | 5 (50) | — |
| Bone marrow | 30 (61) | 0 (0) | 10 (100) | 20 (71) | 2 (20) | |
| Lymph node(s) | 21 (43) | 0 (0) | 4 (40) | 17 (61) | 0 (0) | |
| Bone | 1 (2) | 0 (0) | 0 (0) | 1 (4) | 1 (10) | |
| Liver | 1 (2) | 0 (0) | 0 (0) | 1 (4) | 0 (0) | |
| Spleen | 8 (16) | 0 (0) | 2 (20) | 6 (21) | 0 (0) | |
| CNS | 3 (6) | 0 (0) | 1 (10) | 2 (7) | 0 (0) | |
| Other§ | 5 (10) | 0 (0) | 1 (10) | 4 (14) | 1 (10) |
| Characteristic . | Total . | Skin only . | Systemic only without skin . | Skin and systemic . | Incomplete staging . | P* . |
|---|---|---|---|---|---|---|
| N | 59 | 11 | 10 | 28 | 10 | |
| Age at Dx, median (range), y | 66 (6, 91) | 66 (11, 78) | 61 (26, 84) | 63 (15, 84) | 77 (6, 91) | .98 |
| <60 | 12 (20) | 3 (27) | 4 (40) | 9 (32) | 1 (10) | .84 |
| ≥60 | 47 (80) | 8 (73) | 6 (60) | 19 (68) | 9 (90) | |
| Sex | ||||||
| Female | 12 (20) | 3 (27) | 2 (20) | 5 (18) | 2 (20) | .89 |
| Male | 47 (80) | 8 (73) | 8 (80) | 23 (82) | 8 (80) | |
| Ethnicity | ||||||
| White | 37 (63) | 6 (54) | 6 (60) | 22 (79) | 3 (30) | .20 |
| Other | 9 (15) | 4 (36) | 2 (20) | 3 (10) | 0 (0) | |
| Unknown | 13 (22) | 1 (9) | 2 (20) | 3 (11) | 7 (70) | |
| Karyotype† | ||||||
| Normal | 24 (65) | 9 (100) | 5 (50) | 10 (59) | 0 (0) | .036 |
| Abnormal | 13 (35) | 0 (0) | 5 (50) | 7 (41) | 1 (100) | — |
| Unknown | 22 | 2 | 0 | 11 | 9 | — |
| Other malignancy | ||||||
| Yes | 23 (39) | 3 (27) | 4 (40) | 15 (54) | 1 (10) | .17 |
| None | 15 (25) | 6 (55) | 2 (20) | 6 (21) | 1 (10) | |
| Unknown | 21 (36) | 2 (18) | 4 (40) | 7 (25) | 8 (80) | |
| WBC at Dx, median (range) | 5.3 (1.1, 170.0) | 5.4 (2.6, 10.0) | 5.5 (1.1, 170.0) | 5.2 (1.6, 10.0) | 3.1 | .85 |
| Platelet at Dx, median (range) | 129 (16, 399) | 149 (76, 279) | 90 (29, 399) | 128 (16, 280) | 214 | .41 |
| Hgb at Dx, median (range) | 12.3 (6.9, 16.3) | 13.3 (11.4, 16.3) | 9.7 (6.9, 14.2) | 11.9 (7.6, 16.0) | 13.1 | .019 |
| MCV at Dx, median (range) | 90 (73, 225) | 91.1 (82.0, 111.0) | 89.4 (75.0, 225.0) | 90.0 (73.0, 110.2) | 91.8 | .82 |
| No. of sites, median (range) | 2 (1, 4) | — | — | — | — | — |
| Site of involvement†,‡ | ||||||
| Skin | 39 (80) | 11 (100) | 0 (0) | 28 (100) | 5 (50) | — |
| Bone marrow | 30 (61) | 0 (0) | 10 (100) | 20 (71) | 2 (20) | |
| Lymph node(s) | 21 (43) | 0 (0) | 4 (40) | 17 (61) | 0 (0) | |
| Bone | 1 (2) | 0 (0) | 0 (0) | 1 (4) | 1 (10) | |
| Liver | 1 (2) | 0 (0) | 0 (0) | 1 (4) | 0 (0) | |
| Spleen | 8 (16) | 0 (0) | 2 (20) | 6 (21) | 0 (0) | |
| CNS | 3 (6) | 0 (0) | 1 (10) | 2 (7) | 0 (0) | |
| Other§ | 5 (10) | 0 (0) | 1 (10) | 4 (14) | 1 (10) |
Data are presented as no. (%) unless otherwise indicated. Dx, diagnosis; Hgb, hemoglobin; MCV, mean corpuscular volume; WBC, white blood cell.
Test excludes patients in the Incomplete staging column, who had incomplete data on sites of involvement.
Percentage in Total column excludes patients with incomplete staging.
Multiple sites possible per patient.
Three nasopharynx, 1 cervix, 1 ocular, and 1 rectum.