Lifestyle factors according to mutation status in the total population and in a subpopulation without smoking-related diseases*
| . | Mutation positives . | Nonmutated . | P . | Mutation positives from subpopulation* . | Nonmutated from subpopulation* . | P . |
|---|---|---|---|---|---|---|
| Number | 645 | 19 313 | — | 372 | 12 951 | — |
| Current smoking, n (%) | 126 (20) | 3441 (18) | .2 | 86 (23) | 2426 (19) | .04 |
| Smoking status and load, n (%) | ||||||
| I. Never | 236 (37) | 7444 (39) | .9 | 138 (37) | 5309 (41) | 1.0 |
| II. Former + <10 p-yr | 107 (17) | 3189 (17) | .2 | 57 (15) | 2127 (16) | .7 |
| III. Former + ≥10 p-yr | 138 (21) | 4003 (21) | .9 | 73 (20) | 2216 (17) | .6 |
| IV. Current + <10 p-yr | 21 (3) | 736 (4) | .3 | 16 (4) | 578 (4) | .04 |
| V. Current + ≥10 p-yr trend | 103 (16) | 2663 (14) | .6 | 69 (19) | 1815 (14) | .049 |
| Tobacco consumption, p-yr | 13 (1.2) | 12 (0.17) | .8 | 12 (0.85) | 9.8 (0.17) | .6 |
| Nondrinkers, n (%) | 117 (18) | 4699 (24) | .02 | 66 (18) | 3117 (24) | .1 |
| Alcohol, U/wk | 8.7 (0.43) | 7.1 (0.064) | .09 | 8.8 (0.64) | 6.7 (0.075) | .02 |
| Body mass index, kg/m2 | 27 (0.16) | 27 (0.034) | .02 | 26 (0.20) | 26 (0.039) | .07 |
| . | Mutation positives . | Nonmutated . | P . | Mutation positives from subpopulation* . | Nonmutated from subpopulation* . | P . |
|---|---|---|---|---|---|---|
| Number | 645 | 19 313 | — | 372 | 12 951 | — |
| Current smoking, n (%) | 126 (20) | 3441 (18) | .2 | 86 (23) | 2426 (19) | .04 |
| Smoking status and load, n (%) | ||||||
| I. Never | 236 (37) | 7444 (39) | .9 | 138 (37) | 5309 (41) | 1.0 |
| II. Former + <10 p-yr | 107 (17) | 3189 (17) | .2 | 57 (15) | 2127 (16) | .7 |
| III. Former + ≥10 p-yr | 138 (21) | 4003 (21) | .9 | 73 (20) | 2216 (17) | .6 |
| IV. Current + <10 p-yr | 21 (3) | 736 (4) | .3 | 16 (4) | 578 (4) | .04 |
| V. Current + ≥10 p-yr trend | 103 (16) | 2663 (14) | .6 | 69 (19) | 1815 (14) | .049 |
| Tobacco consumption, p-yr | 13 (1.2) | 12 (0.17) | .8 | 12 (0.85) | 9.8 (0.17) | .6 |
| Nondrinkers, n (%) | 117 (18) | 4699 (24) | .02 | 66 (18) | 3117 (24) | .1 |
| Alcohol, U/wk | 8.7 (0.43) | 7.1 (0.064) | .09 | 8.8 (0.64) | 6.7 (0.075) | .02 |
| Body mass index, kg/m2 | 27 (0.16) | 27 (0.034) | .02 | 26 (0.20) | 26 (0.039) | .07 |
Data are shown as raw mean (SE) for continuous variables. P values in bold are <.05
p-yr, pack-years.
Subpopulation of no smoking-related diseases: no history of acute myocardial infarction, ischemic heart disease, ischemic cerebrovascular disease, cancer, or diabetes and no use of asthma/bronchitis medication, antihypertensive medication, or diabetes medication.