Summary of adverse events
| Adverse events . | N (%) . |
|---|---|
| Hematological toxicity | |
| Leukopenia | |
| Grade 1 | 2 (8) |
| Neutropenia | |
| Grade 1 | 1 (4) |
| Nonhematological toxicity | |
| Rash | |
| Grade 1 | 3 (12) |
| Grade 3 | 1 (4) |
| Pruritus | |
| Grade 1 | 5 (20) |
| Constipation | |
| Grade 1 | 8 (32) |
| Grade 2 | 2 (8) |
| Irregular menses* | |
| Grade 1 | 1 (12.5) |
| Grade 2 | 1 (12.5) |
| Decreased libido | |
| Grade 1 | 3 (12) |
| Erectile dysfunction† | |
| Grade 1 | 1 (5.8) |
| Pneumonitis | |
| Grade 1 | 1 (4) |
| Grade 2 | 1 (4) |
| Grade 5 | 1 (4) |
| Neuropathy: motor | |
| Grade 1 | 2 (8) |
| Neuropathy: sensory | |
| Grade 1 | 2 (8) |
| Grade 2 | 2 (8) |
| HBV reactivation | 1 (4) |
| Nausea | |
| Grade 1 | 4 (16) |
| Glucose intolerance | |
| Grade 1 | 2 (8) |
| Grade 2 | 1 (4) |
| ALT elevation | |
| Grade 1 | 3 (12) |
| Adverse events . | N (%) . |
|---|---|
| Hematological toxicity | |
| Leukopenia | |
| Grade 1 | 2 (8) |
| Neutropenia | |
| Grade 1 | 1 (4) |
| Nonhematological toxicity | |
| Rash | |
| Grade 1 | 3 (12) |
| Grade 3 | 1 (4) |
| Pruritus | |
| Grade 1 | 5 (20) |
| Constipation | |
| Grade 1 | 8 (32) |
| Grade 2 | 2 (8) |
| Irregular menses* | |
| Grade 1 | 1 (12.5) |
| Grade 2 | 1 (12.5) |
| Decreased libido | |
| Grade 1 | 3 (12) |
| Erectile dysfunction† | |
| Grade 1 | 1 (5.8) |
| Pneumonitis | |
| Grade 1 | 1 (4) |
| Grade 2 | 1 (4) |
| Grade 5 | 1 (4) |
| Neuropathy: motor | |
| Grade 1 | 2 (8) |
| Neuropathy: sensory | |
| Grade 1 | 2 (8) |
| Grade 2 | 2 (8) |
| HBV reactivation | 1 (4) |
| Nausea | |
| Grade 1 | 4 (16) |
| Glucose intolerance | |
| Grade 1 | 2 (8) |
| Grade 2 | 1 (4) |
| ALT elevation | |
| Grade 1 | 3 (12) |