Table 2.

CI values of synergy experiments in U266 cells

TAK-243
25 nM50 nM100 nM200 nM
Panobinostat, nM     
 3.125 0.26 0.256 0.297  
 6.25 0.447 0.37 0.323  
 12.5 0.513 0.521 0.465  
Melphalan, nM     
 250  0.3127 0.2568 0.4683 
 500  0.3496 0.3852 0.4748 
 1000  0.3770 0.4826 0.5864 
Doxorubicin, nM     
 62.5  0.3762 0.3582 0.4605 
 125  0.5397 0.4085 0.613 
 250  0.7009 0.6571 0.7471 
TAK-243
25 nM50 nM100 nM200 nM
Panobinostat, nM     
 3.125 0.26 0.256 0.297  
 6.25 0.447 0.37 0.323  
 12.5 0.513 0.521 0.465  
Melphalan, nM     
 250  0.3127 0.2568 0.4683 
 500  0.3496 0.3852 0.4748 
 1000  0.3770 0.4826 0.5864 
Doxorubicin, nM     
 62.5  0.3762 0.3582 0.4605 
 125  0.5397 0.4085 0.613 
 250  0.7009 0.6571 0.7471 
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