Hallmark gene sets identified from the Molecular Signatures Database using gene expression data from MM1.S cells exposed to TAK-243
| Gene sets . |
|---|
| Upregulated |
| HALLMARK_TNFA_SIGNALING_VIA_NFκB |
| HALLMARK_UNFOLDED_PROTEIN_RESPONSE |
| HALLMARK_P53_PATHWAY |
| HALLMARK_APOPTOSIS |
| HALLMARK_INFLAMMATORY_RESPONSE |
| HALLMARK_HYPOXIA |
| HALLMARK_MYC_TARGETS_V2 |
| Downregulated |
| HALLMARK_PEROXISOME |
| HALLMARK_BILE_ACID_METABOLISM |
| HALLMARK_E2F_TARGETS |
| HALLMARK_FATTY_ACID_METABOLISM |
| HALLMARK_OXIDATIVE_PHOSPHORYLATION |
| HALLMARK_HEME_METABOLISM |
| Gene sets . |
|---|
| Upregulated |
| HALLMARK_TNFA_SIGNALING_VIA_NFκB |
| HALLMARK_UNFOLDED_PROTEIN_RESPONSE |
| HALLMARK_P53_PATHWAY |
| HALLMARK_APOPTOSIS |
| HALLMARK_INFLAMMATORY_RESPONSE |
| HALLMARK_HYPOXIA |
| HALLMARK_MYC_TARGETS_V2 |
| Downregulated |
| HALLMARK_PEROXISOME |
| HALLMARK_BILE_ACID_METABOLISM |
| HALLMARK_E2F_TARGETS |
| HALLMARK_FATTY_ACID_METABOLISM |
| HALLMARK_OXIDATIVE_PHOSPHORYLATION |
| HALLMARK_HEME_METABOLISM |