cALD patient and transplant characteristics (N = 66)
. | Data . |
---|---|
Age, y | 8.3 (4.4-47.1) |
Baseline Loes score | 9 (1-19.5) |
Baseline gadolinium intensity score | 2 (1-3) |
CSF total protein, mg/dL | 37 (11-186) |
Preparative regimen, n | |
Nonmyeloablative | 14 |
Myeloablative | 52 |
Stem cell source, n | |
Umbilical cord blood | 34 |
Unrelated donor | 11 |
Sibling marrow donor | 19 |
Parent donor | 2 |
Total nucleated cell dose, 108 cells/kg | 0.90 (0.24-8.25) |
CD34 dose, 106 cells/kg | 1.43 (0.11-15.97) |
ANC recovery, d | 16 (9-45) |
Platelet recovery, d | 34 (13-244) |
Day-60 CD15 chimerism, % | 100 (14.1-100) |
Day-60 CD3 chimerism, % | 93.5 (0-100) |
. | Data . |
---|---|
Age, y | 8.3 (4.4-47.1) |
Baseline Loes score | 9 (1-19.5) |
Baseline gadolinium intensity score | 2 (1-3) |
CSF total protein, mg/dL | 37 (11-186) |
Preparative regimen, n | |
Nonmyeloablative | 14 |
Myeloablative | 52 |
Stem cell source, n | |
Umbilical cord blood | 34 |
Unrelated donor | 11 |
Sibling marrow donor | 19 |
Parent donor | 2 |
Total nucleated cell dose, 108 cells/kg | 0.90 (0.24-8.25) |
CD34 dose, 106 cells/kg | 1.43 (0.11-15.97) |
ANC recovery, d | 16 (9-45) |
Platelet recovery, d | 34 (13-244) |
Day-60 CD15 chimerism, % | 100 (14.1-100) |
Day-60 CD3 chimerism, % | 93.5 (0-100) |
All data are median (range), unless noted otherwise.