Blood group modulates platelet translocating behavior on VWF
| . | Mean ± SD . | P . | |
|---|---|---|---|
| Type O (n = 33) . | Non-O (n = 54) . | ||
| Platelet tracks | 273 ± 130 | 272 ± 95 | .62 |
| Proportion of all platelets stably adhered to VWF surface | 0.55 ± 0.1 | 0.63 ± 0.1 | .009 |
| Mean translocation distance, µm | 5.77 ± 1.8 | 4.74 ± 1.4 | .037 |
| Mean translocating velocity, µm/s | 4.6 ± 2.1 | 3.4 ± 1.7 | .002 |
| Rate of platelet adhesion, 1/s (Ron) | 0.11 ± 0.06 | 0.16 ± 0.05 | .011 |
| Rate of platelet detachment, 1/s (Roff) | 0.06 ± 0.03 | 0.08 ± 0.04 | .39 |
| Platelet count, ×109/L | 217 ± 57 | 215 ± 55 | .72 |
| Haematocrit, % | 39.9 ± 4.2 | 38.5 ± 3.9 | .19 |
| Male sex, % | 55 | 39 | .16 |
| CD41 (n = 20 non-O; n = 20 type O) | 62 600 ± 13 600 | 61 600 ± 11 900 | .81 |
| CD42b (n = 20 non-O; n = 20 type O) | 46 800 ± 6 800 | 44 300 ± 8 300 | .33 |
| VWF, IU/dL | 51.0 ± 32.3 | 62.1 ± 34.7 | .14 |
| . | Mean ± SD . | P . | |
|---|---|---|---|
| Type O (n = 33) . | Non-O (n = 54) . | ||
| Platelet tracks | 273 ± 130 | 272 ± 95 | .62 |
| Proportion of all platelets stably adhered to VWF surface | 0.55 ± 0.1 | 0.63 ± 0.1 | .009 |
| Mean translocation distance, µm | 5.77 ± 1.8 | 4.74 ± 1.4 | .037 |
| Mean translocating velocity, µm/s | 4.6 ± 2.1 | 3.4 ± 1.7 | .002 |
| Rate of platelet adhesion, 1/s (Ron) | 0.11 ± 0.06 | 0.16 ± 0.05 | .011 |
| Rate of platelet detachment, 1/s (Roff) | 0.06 ± 0.03 | 0.08 ± 0.04 | .39 |
| Platelet count, ×109/L | 217 ± 57 | 215 ± 55 | .72 |
| Haematocrit, % | 39.9 ± 4.2 | 38.5 ± 3.9 | .19 |
| Male sex, % | 55 | 39 | .16 |
| CD41 (n = 20 non-O; n = 20 type O) | 62 600 ± 13 600 | 61 600 ± 11 900 | .81 |
| CD42b (n = 20 non-O; n = 20 type O) | 46 800 ± 6 800 | 44 300 ± 8 300 | .33 |
| VWF, IU/dL | 51.0 ± 32.3 | 62.1 ± 34.7 | .14 |
Data were analyzed using Mann-Whitney U tests to account for their nonparametric distribution.
SD, standard deviation.