Symptomatic, radiologic, and cytologic responses in 28 patients with BNS treated with single-agent ibrutinib
| . | n/N (%) . | |||
|---|---|---|---|---|
| 3 mo . | 6 mo . | 12 mo . | Best response . | |
| Symptomatic | ||||
| Resolved | 1/26 (4) | 3/20 (15) | 2/10 (20) | 5/28 (18) |
| Improved | 21/26 (81) | 15/20 (75) | 7/10 (70) | 19/28 (68) |
| Unchanged | 4/26 (15) | 2/20 (10) | 1/10 (10) | 4/28 (14) |
| Radiologic | ||||
| Resolved | 0/15 (0) | 1/9 (11) | 2/8 (25) | 2/18 (11) |
| Improved | 9/15 (60) | 7/9 (78) | 6/8 (75) | 13/18 (72) |
| Unchanged | 6/15 (40) | 1/9 (11) | 0/8 (0) | 3/18 (17) |
| Cytologic | ||||
| Cleared | 7/12 (58) | 2/7 (29) | 0/1 (0) | 8/17 (47) |
| Persistent | 5/12 (42) | 5/7 (71) | 1/1 (100) | 9/17 (53) |
| . | n/N (%) . | |||
|---|---|---|---|---|
| 3 mo . | 6 mo . | 12 mo . | Best response . | |
| Symptomatic | ||||
| Resolved | 1/26 (4) | 3/20 (15) | 2/10 (20) | 5/28 (18) |
| Improved | 21/26 (81) | 15/20 (75) | 7/10 (70) | 19/28 (68) |
| Unchanged | 4/26 (15) | 2/20 (10) | 1/10 (10) | 4/28 (14) |
| Radiologic | ||||
| Resolved | 0/15 (0) | 1/9 (11) | 2/8 (25) | 2/18 (11) |
| Improved | 9/15 (60) | 7/9 (78) | 6/8 (75) | 13/18 (72) |
| Unchanged | 6/15 (40) | 1/9 (11) | 0/8 (0) | 3/18 (17) |
| Cytologic | ||||
| Cleared | 7/12 (58) | 2/7 (29) | 0/1 (0) | 8/17 (47) |
| Persistent | 5/12 (42) | 5/7 (71) | 1/1 (100) | 9/17 (53) |