Table 1.

Risk factor for VTE in cancer patients

Risk factors
Patient-related 
 Advanced age 
 Comorbidities 
 Immobilization or hospitalization 
 Previous VTE 
 Hereditary thrombophilia 
Tumor-related 
 Tumor type 
  • Very high risk: gastric, pancreas, brain 
  • High risk: lung, hematologic, gynecologic, renal, bladder 
 Cancer stage 
 Histological tumor grade 
 Localized tumor compression 
Treatment-related 
 Chemotherapy (eg cisplatin-based, antiangiogenesis agents) 
 Hormonal therapy 
 Red blood cell transfusions and erythropoiesis-stimulating agents 
 Surgery 
 Radiotherapy 
 Central venous catheters 
Risk factors
Patient-related 
 Advanced age 
 Comorbidities 
 Immobilization or hospitalization 
 Previous VTE 
 Hereditary thrombophilia 
Tumor-related 
 Tumor type 
  • Very high risk: gastric, pancreas, brain 
  • High risk: lung, hematologic, gynecologic, renal, bladder 
 Cancer stage 
 Histological tumor grade 
 Localized tumor compression 
Treatment-related 
 Chemotherapy (eg cisplatin-based, antiangiogenesis agents) 
 Hormonal therapy 
 Red blood cell transfusions and erythropoiesis-stimulating agents 
 Surgery 
 Radiotherapy 
 Central venous catheters 

Adapted from Ay et al.55  Shown are risk factors for VTE that may be considered in the decision to stop or continue anticoagulation after an initial 3- to 6-month treatment of VTE in cancer patients.

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