Table 2. Selected trials highlighting... | American Society of Hematology

Table 2.

Selected trials highlighting prevalence of geriatric impairments among older patients with hematologic malignancies

Disease type/setting	No. patients	ADLs, %	IADLs, %	Physical performance, %	Cognitive, %	Mood, %	Comorbidity burden, %	Nutritional status, %
Chronic lymphocytic leukemia⁸	75	n/a	19	63	49	n/a	36	n/a
Multiple myeloma¹⁰	869	14	18	n/a	n/a	n/a	17	n/a
Acute myeloid leukemia²⁰	54	48	41	54	32	39	46	n/a
Acute myeloid leukemia/myelodysplastic syndrome⁷	195	34	n/a	55	9	14	n/a	n/a
Myelodysplastic syndrome¹⁴	98	29	34	31	11	32	23	27
Myelodysplastic syndrome¹⁹	455	n/a	45	35*	n/a	n/a	58	n/a
Non-Hodgkin lymphoma¹¹	84	12	n/a	n/a	n/a	n/a	50	n/a
Non-Hodgkin lymphoma²²	143	18	21	n/a	n/a	n/a	56	n/a
Non-Hodgkin lymphoma²³	70	n/a	n/a	n/a	28	41	n/a	36
Bone marrow transplantation (preallogeneic transplant evaluation, mixed population, age ≥ 50 y)¹²	203	7	40	33	n/a	56	55	58
Bone marrow transplantation (preautologous transplant evaluation, age ≥ 50 y)²⁴	184	n/a	36	15	3	35	33	n/a

Disease type/setting	No. patients	ADLs, %	IADLs, %	Physical performance, %	Cognitive, %	Mood, %	Comorbidity burden, %	Nutritional status, %
Chronic lymphocytic leukemia⁸	75	n/a	19	63	49	n/a	36	n/a
Multiple myeloma¹⁰	869	14	18	n/a	n/a	n/a	17	n/a
Acute myeloid leukemia²⁰	54	48	41	54	32	39	46	n/a
Acute myeloid leukemia/myelodysplastic syndrome⁷	195	34	n/a	55	9	14	n/a	n/a
Myelodysplastic syndrome¹⁴	98	29	34	31	11	32	23	27
Myelodysplastic syndrome¹⁹	455	n/a	45	35*	n/a	n/a	58	n/a
Non-Hodgkin lymphoma¹¹	84	12	n/a	n/a	n/a	n/a	50	n/a
Non-Hodgkin lymphoma²²	143	18	21	n/a	n/a	n/a	56	n/a
Non-Hodgkin lymphoma²³	70	n/a	n/a	n/a	28	41	n/a	36
Bone marrow transplantation (preallogeneic transplant evaluation, mixed population, age ≥ 50 y)¹²	203	7	40	33	n/a	56	55	58
Bone marrow transplantation (preautologous transplant evaluation, age ≥ 50 y)²⁴	184	n/a	36	15	3	35	33	n/a

Tests and thresholds for impairment varied for physical performance, cognitive function, mood, comorbidity burden, and nutritional status.

n/a, not assessed or reported.

Prevalence estimate refers to gait speed < 4.82 seconds.