Mouse studies on tumor-derived, TF+ EVs and venous thrombosis
| Reference . | Mouse type . | Cancer cell type . | Tumor site . | Thrombosis model . | Observation . |
|---|---|---|---|---|---|
| 13 | C57BL/6 | Panc02 | SC | Mesenteric venules FeCl3 | Shortened time to occlusion |
| 13 | C57BL/6 | Panc02 | SC | Cremaster venules laser injury | Accumulation of tumor-derived TF+ EVs at the site of injury |
| 32 | C57BL/6 | Panc02 | SC | IVC stenosis | Increased incidence and weight of thrombi |
| 16 | Nude | HPAF-II | Orthotopic | IVC stenosis | No enhancement of thrombosis |
| 16 | Nude | HPAF-II | Orthotopic | Saphenous vein FeCl3 | Shortened time to occlusion |
| 33 | Nude | BxPc-3 | Orthotopic | IVC stenosis | Increased thrombus area using ultrasound but no increase in incidence of thrombosis |
| 15 | Nude | BxPc-3 | Orthotopic | IVC stasis | Increased weight of thrombus |
| Reference . | Mouse type . | Cancer cell type . | Tumor site . | Thrombosis model . | Observation . |
|---|---|---|---|---|---|
| 13 | C57BL/6 | Panc02 | SC | Mesenteric venules FeCl3 | Shortened time to occlusion |
| 13 | C57BL/6 | Panc02 | SC | Cremaster venules laser injury | Accumulation of tumor-derived TF+ EVs at the site of injury |
| 32 | C57BL/6 | Panc02 | SC | IVC stenosis | Increased incidence and weight of thrombi |
| 16 | Nude | HPAF-II | Orthotopic | IVC stenosis | No enhancement of thrombosis |
| 16 | Nude | HPAF-II | Orthotopic | Saphenous vein FeCl3 | Shortened time to occlusion |
| 33 | Nude | BxPc-3 | Orthotopic | IVC stenosis | Increased thrombus area using ultrasound but no increase in incidence of thrombosis |
| 15 | Nude | BxPc-3 | Orthotopic | IVC stasis | Increased weight of thrombus |
SC, subcutaneous.