Accuracy of PTP assessment and D-dimer testing in cancer and non-cancer patients with suspected DVT
| Reference . | Patients with cancer . | Patients without cancer . | ||
|---|---|---|---|---|
| Low PTP and negative D-dimer . | Unlikely PTP and negative D-dimer . | Low PTP and negative D-dimer . | Unlikely PTP and negative D-dimer . | |
| Carrier et al15 | ||||
| N (%) | 12 (6.0) | 24 (12.0) | 557 (22.3) | 894 (35.8) |
| Sensitivity, % (95% CI) | 100 (31.0-100) | 100 (59.8-100) | 95.0 (81.8-99.1) | 91.7 (82.1-96.6) |
| Specificity, % (95% CI) | 46.2 (27.1-66.3) | 57.1 (41.1-71.9) | 62.9 (59.6-66.1) | 70.4 (67.8-72.9) |
| NPV, % (95% CI) | 100 (69.8-100) | 100 (82.8-99.6) | 99.6 (98.6-99.9) | 99.3 (98.5-99.7) |
| Di Nisio et al16 | ||||
| N (%) | 22 (9.0) | — | 651 (35.7) | — |
| Sensitivity, % (95% CI) | 100 (51.0-100) | — | 86.0 (78.0-92.0) | — |
| Specificity, % (95% CI) | 58.0 (42.0-72.0) | — | 66.0 (63.0-69.0) | — |
| NPV, % (95% CI) | 100 (85.0-100) | — | 98.0 (97.0-99.0) | — |
| Reference . | Patients with cancer . | Patients without cancer . | ||
|---|---|---|---|---|
| Low PTP and negative D-dimer . | Unlikely PTP and negative D-dimer . | Low PTP and negative D-dimer . | Unlikely PTP and negative D-dimer . | |
| Carrier et al15 | ||||
| N (%) | 12 (6.0) | 24 (12.0) | 557 (22.3) | 894 (35.8) |
| Sensitivity, % (95% CI) | 100 (31.0-100) | 100 (59.8-100) | 95.0 (81.8-99.1) | 91.7 (82.1-96.6) |
| Specificity, % (95% CI) | 46.2 (27.1-66.3) | 57.1 (41.1-71.9) | 62.9 (59.6-66.1) | 70.4 (67.8-72.9) |
| NPV, % (95% CI) | 100 (69.8-100) | 100 (82.8-99.6) | 99.6 (98.6-99.9) | 99.3 (98.5-99.7) |
| Di Nisio et al16 | ||||
| N (%) | 22 (9.0) | — | 651 (35.7) | — |
| Sensitivity, % (95% CI) | 100 (51.0-100) | — | 86.0 (78.0-92.0) | — |
| Specificity, % (95% CI) | 58.0 (42.0-72.0) | — | 66.0 (63.0-69.0) | — |
| NPV, % (95% CI) | 100 (85.0-100) | — | 98.0 (97.0-99.0) | — |