Table 1.

Maternal and fetal complications in women with SCD

Complications
Maternal complications of pregnancy 
 Increased maternal mortality 
 Hypertension syndromes—preeclampsia and eclampsia 
 Venothromboembolism 
 Increased pain (acute, chronic, or recurrent acute) and other SCD-related complications, including infection, acute chest syndrome, acute exacerbation of anemia, and acute splenic sequestration 
 Worsening steady-state anemia 
 Proteinuria, worsening of renal disease 
 Hepatic dysfunction, worsening of hepatic disease 
Fetal complications of pregnancy 
 Mortality 
 Prematurity 
 Growth problems—intrauterine growth restriction and small for gestational age 
Complications
Maternal complications of pregnancy 
 Increased maternal mortality 
 Hypertension syndromes—preeclampsia and eclampsia 
 Venothromboembolism 
 Increased pain (acute, chronic, or recurrent acute) and other SCD-related complications, including infection, acute chest syndrome, acute exacerbation of anemia, and acute splenic sequestration 
 Worsening steady-state anemia 
 Proteinuria, worsening of renal disease 
 Hepatic dysfunction, worsening of hepatic disease 
Fetal complications of pregnancy 
 Mortality 
 Prematurity 
 Growth problems—intrauterine growth restriction and small for gestational age 
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