Table 3.

CAPS classification criteria54 

ClassificationCriteria
Definite CAPS 1. Evidence of involvement of 3 or more organs, systems, and/or tissues 
2. Development of manifestations simultaneously or in <1 wk 
3. Confirmation by histopathology of small vessel occlusion in at least 1 organ or tissue 
4. Laboratory confirmation of persistent aPL 
Probable CAPS All 4 criteria except for only 2 organs, systems, and/or tissues involved 
All 4 criteria except for the absence of laboratory confirmation of aPL 
All 4 criteria except for the absence of histopathologic confirmation of small vessel occlusion 
All 4 criteria except for the development of a third event in >1 wk but <1 mo despite anticoagulation 
ClassificationCriteria
Definite CAPS 1. Evidence of involvement of 3 or more organs, systems, and/or tissues 
2. Development of manifestations simultaneously or in <1 wk 
3. Confirmation by histopathology of small vessel occlusion in at least 1 organ or tissue 
4. Laboratory confirmation of persistent aPL 
Probable CAPS All 4 criteria except for only 2 organs, systems, and/or tissues involved 
All 4 criteria except for the absence of laboratory confirmation of aPL 
All 4 criteria except for the absence of histopathologic confirmation of small vessel occlusion 
All 4 criteria except for the development of a third event in >1 wk but <1 mo despite anticoagulation 
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