Key points in management of adults with SCN
| Annual ACR and protein/creatinine ratio |
| Patients with SCN are more likely to develop AKI during intercurrent illnesses |
| Avoid NSAIDs in patients with SCN |
| Further investigation if protein/creatinine ratio > 50 mg/mmol or eGFR < 60 mL/min |
| ACEi/ARB if persistent proteinuria (>50 mg/mmol) |
| Consider HU if proteinuria and/or CKD |
| Meticulous blood pressure control (<130/80 mmHg) |
| Consider ESAs and HU if anemia is worsening |
| Consider early renal transplantation in ESRF |
| Annual ACR and protein/creatinine ratio |
| Patients with SCN are more likely to develop AKI during intercurrent illnesses |
| Avoid NSAIDs in patients with SCN |
| Further investigation if protein/creatinine ratio > 50 mg/mmol or eGFR < 60 mL/min |
| ACEi/ARB if persistent proteinuria (>50 mg/mmol) |
| Consider HU if proteinuria and/or CKD |
| Meticulous blood pressure control (<130/80 mmHg) |
| Consider ESAs and HU if anemia is worsening |
| Consider early renal transplantation in ESRF |
AKI, acute kidney injury; NSAIDs, nonsteroidal anti-inflammatory agents.