Table 3.

Making decisions about screening: when is screening justified

Criterion
The condition should be an important health problem (either sufficiently prevalent or having significant consequences) 
Individuals with a positive screening test would get a different management than those with a negative test 
The condition being screened for should have a natural history that is understood and a recognized latent or early symptomatic stage 
There should be an effective treatment/management for the condition that improves outcomes if administered before the condition is clinically apparent 
The improvement in outcomes based on management according to screening results should outweigh harms of screening 
There should be high- or moderate-quality evidence for a sufficient accuracy of the test (acceptable low rates of false-positives and -negatives) 
Screening should be cost-effective 
Screening should be acceptable to patients 
Screening should be feasible to implement 
Criterion
The condition should be an important health problem (either sufficiently prevalent or having significant consequences) 
Individuals with a positive screening test would get a different management than those with a negative test 
The condition being screened for should have a natural history that is understood and a recognized latent or early symptomatic stage 
There should be an effective treatment/management for the condition that improves outcomes if administered before the condition is clinically apparent 
The improvement in outcomes based on management according to screening results should outweigh harms of screening 
There should be high- or moderate-quality evidence for a sufficient accuracy of the test (acceptable low rates of false-positives and -negatives) 
Screening should be cost-effective 
Screening should be acceptable to patients 
Screening should be feasible to implement 

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