Table 2. Hematological parameters of... | American Society of Hematology

Table 2.

Hematological parameters of experimental mice

Construct	Mouse	Survival, d	RBC, ×10¹²/L	WBC, ×10⁹/L	Spleen weight, mg	Blasts BM, %	Blasts spleen, %	Blasts PB, %	Lymphoid/ myeloid ratio in PB
GFP	1	90*	6.0	4.5	150	0	0	0	5
GFP	2	90*	4.8	3.2	200	0	0	0	2
GFP	3	90*	5.0	3.6	200	0	0	0	2
Cdx4	4	423	1.5	2.3	164	57	>95	56	<0.01
Cdx4	5	178	0.7	2.6	449	>95	>95	61	0.02
Cdx4	6	222	1.3†	2.5†	n.d.	n.d.	n.d.	52†	<0.01†
Cdx4	7	504	0.6	1.2	401	35	62	52	<0.01
Cdx4	8	364	12	9.1	129	20	35	52	0.8
Cdx4	9	364	12	8.9	134	11	39	29	0.9
Cdx4	10	341	0.9†	85†	n.d.	n.d.	n.d.	63†	0.02†
Cdx4	11	276	2.7†	3.4†	n.d.	n.d.	n.d.	50†	0.1†
Cdx4	12	257	3.4	2.9	505	27	39	2	<0.01
Cdx4	13	472	6.1	5.5	345	65	75	25	<0.01
Cdx4	14	245	10†	4.0†	398	n.d.	n.d.	66†	0.1†
Cdx4	15	154	8.5	3.3	296	43	55	24	<0.01

Construct	Mouse	Survival, d	RBC, ×10¹²/L	WBC, ×10⁹/L	Spleen weight, mg	Blasts BM, %	Blasts spleen, %	Blasts PB, %	Lymphoid/ myeloid ratio in PB
GFP	1	90*	6.0	4.5	150	0	0	0	5
GFP	2	90*	4.8	3.2	200	0	0	0	2
GFP	3	90*	5.0	3.6	200	0	0	0	2
Cdx4	4	423	1.5	2.3	164	57	>95	56	<0.01
Cdx4	5	178	0.7	2.6	449	>95	>95	61	0.02
Cdx4	6	222	1.3†	2.5†	n.d.	n.d.	n.d.	52†	<0.01†
Cdx4	7	504	0.6	1.2	401	35	62	52	<0.01
Cdx4	8	364	12	9.1	129	20	35	52	0.8
Cdx4	9	364	12	8.9	134	11	39	29	0.9
Cdx4	10	341	0.9†	85†	n.d.	n.d.	n.d.	63†	0.02†
Cdx4	11	276	2.7†	3.4†	n.d.	n.d.	n.d.	50†	0.1†
Cdx4	12	257	3.4	2.9	505	27	39	2	<0.01
Cdx4	13	472	6.1	5.5	345	65	75	25	<0.01
Cdx4	14	245	10†	4.0†	398	n.d.	n.d.	66†	0.1†
Cdx4	15	154	8.5	3.3	296	43	55	24	<0.01

Healthy control mice were euthanized at day 90 post transplantation.

L/M, lymphoid/myeloid ratio in PB; n.d., not determined; RBC, red blood cell; WBC, white blood cell.

Control mice were euthanized for analysis.

†

As spleen, BM, and PB of some mice could not be analyzed because of the sudden death of the animals; the results of the respective last PB analysis are indicated.

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