Table 1.

Patient characteristics (N = 26 695)

VariablesData
Sex  
 Female 11 113 (41.6) 
 Male 15 578 (58.3) 
Age, y  
 Median 45 
 Range 16-69 
PS  
 0-1 21 567 (80.8) 
 ≥2 1 638 (6.1) 
 Missing 3 490 (13.1) 
HCT-CI  
 ≤2 14 906 (55.8) 
 ≥3 2 275 (8.5) 
 Missing 9 514 (35.7) 
Disease  
 AML/MDS 13 613 (51.0) 
 ALL 5 129 (19.2) 
 ATL 1 153 (4.3) 
 CML 2 141 (8.0) 
 NHL 2 218 (8.3) 
 AA 1 024 (3.9) 
 Other 1 417 (5.3) 
Disease risk  
 Standard 14 088 (52.7) 
 High 12 607 (47.2) 
Pretransplant therapy period, mo  
 Median 8.2 
 Range 1.2-779.3 
Donor source  
 Rel-BM 4 899 (18.4) 
 Rel-PB 5 389 (20.2) 
 UR-BM 10 801 (40.5) 
 UR-CB 5 425 (20.3) 
HLA mismatch  
 No 13 969 (52.3) 
 Yes 12 726 (47.7) 
Sex mismatch  
 No 13 136 (49.2) 
 M to F 5 729 (21.4) 
 F to M 5 657 (21.1) 
ABO mismatch  
 No 12 060 (45.1) 
 Minor 5 169 (19.3) 
 Major 4 694 (17.5) 
 Both 2 408 (9.0) 
Conditioning regimens  
 MAC 16 480 (61.7) 
 RIC 8 277 (31.0) 
GVHD prophylaxis  
 CyA based 12 612 (47.2) 
 Tac based 14 083 (52.8) 
Follow-up period, mo  
 Median 58.7 
 Range 1.4-306.6 
Transplant year  
 2008 or before 12 495 (46.8) 
 2009 or later 14 200 (53.2) 
VariablesData
Sex  
 Female 11 113 (41.6) 
 Male 15 578 (58.3) 
Age, y  
 Median 45 
 Range 16-69 
PS  
 0-1 21 567 (80.8) 
 ≥2 1 638 (6.1) 
 Missing 3 490 (13.1) 
HCT-CI  
 ≤2 14 906 (55.8) 
 ≥3 2 275 (8.5) 
 Missing 9 514 (35.7) 
Disease  
 AML/MDS 13 613 (51.0) 
 ALL 5 129 (19.2) 
 ATL 1 153 (4.3) 
 CML 2 141 (8.0) 
 NHL 2 218 (8.3) 
 AA 1 024 (3.9) 
 Other 1 417 (5.3) 
Disease risk  
 Standard 14 088 (52.7) 
 High 12 607 (47.2) 
Pretransplant therapy period, mo  
 Median 8.2 
 Range 1.2-779.3 
Donor source  
 Rel-BM 4 899 (18.4) 
 Rel-PB 5 389 (20.2) 
 UR-BM 10 801 (40.5) 
 UR-CB 5 425 (20.3) 
HLA mismatch  
 No 13 969 (52.3) 
 Yes 12 726 (47.7) 
Sex mismatch  
 No 13 136 (49.2) 
 M to F 5 729 (21.4) 
 F to M 5 657 (21.1) 
ABO mismatch  
 No 12 060 (45.1) 
 Minor 5 169 (19.3) 
 Major 4 694 (17.5) 
 Both 2 408 (9.0) 
Conditioning regimens  
 MAC 16 480 (61.7) 
 RIC 8 277 (31.0) 
GVHD prophylaxis  
 CyA based 12 612 (47.2) 
 Tac based 14 083 (52.8) 
Follow-up period, mo  
 Median 58.7 
 Range 1.4-306.6 
Transplant year  
 2008 or before 12 495 (46.8) 
 2009 or later 14 200 (53.2) 

Unless otherwise indicated, data are n (%).

AA, aplastic anemia; ALL, acute lymphoblastic leukemia; AML, acute myelogenous leukemia; ATL, adult T-cell lymphoma/leukemia; CML, chronic myelogenous leukemia; CyA, cyclosporine; F, female; GVHD, graft-versus-host disease; M, male; MAC, myeloablative conditioning; MDS, myelodysplastic syndrome; NHL, non-Hodgkin lymphoma; Rel-BM, bone marrow from relative; Rel-PB, peripheral blood stem cells from relative; RIC, reduced-intensity conditioning; Tac, tacrolimus; UR-BM, bone marrow from unrelated donor; UR-CB, cord blood from unrelated donor.

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