Parameters of thromboelastography in PRP from hemophilia mice
| . | WT (n = 9) . | PN-1−/− (n = 9) . | F8−/− (n = 9) . | F8−/−/PN-1−/− (n = 9) . |
|---|---|---|---|---|
| Clotting time, s | 216.8 ± 33.21 | 225.7 ± 26.99 | 246.6 ± 39.84 | 241.2 ± 60.42 |
| MCF, mm | 56.56 ± 9.14 | 56.33 ± 6.44 | 19.33 ± 15.39 | 35.56 ± 16.61* |
| LOT, s | 2139 ± 555.0 | 2383 ± 1001 | 796.3 ± 583.3 | 1498 ± 1019* |
| Lysis time, s | 3079 ± 896.2 | 3609 ± 1557 | 2066 ± 479.1 | 2639 ± 1393 |
| Maximum clot elasticity | 137.6 ± 42.37 | 133.2 ± 30.32 | 28.89 ± 31.61 | 65.78 ± 51.10 |
| . | WT (n = 9) . | PN-1−/− (n = 9) . | F8−/− (n = 9) . | F8−/−/PN-1−/− (n = 9) . |
|---|---|---|---|---|
| Clotting time, s | 216.8 ± 33.21 | 225.7 ± 26.99 | 246.6 ± 39.84 | 241.2 ± 60.42 |
| MCF, mm | 56.56 ± 9.14 | 56.33 ± 6.44 | 19.33 ± 15.39 | 35.56 ± 16.61* |
| LOT, s | 2139 ± 555.0 | 2383 ± 1001 | 796.3 ± 583.3 | 1498 ± 1019* |
| Lysis time, s | 3079 ± 896.2 | 3609 ± 1557 | 2066 ± 479.1 | 2639 ± 1393 |
| Maximum clot elasticity | 137.6 ± 42.37 | 133.2 ± 30.32 | 28.89 ± 31.61 | 65.78 ± 51.10 |
Means ± SD. A 2-way ANOVA test, followed by a multiple comparison test, was used.
P < .05 vs F8−/− mice.