Table 1.

Sickle cell screening in US3 and the post-US3 period

Region of UgandaUS3 (1 year) (97 631 samples)Post-US3 (3 years) (112 352 samples)
SCT (%)SCD (%)SCT (%)SCD (%)
Central 1 1896 (12.9) 69 (0.5) 2497 (13.1) 144 (0.8) 
Central 2 1566 (14.1) 94 (0.8) 1646 (14.4) 128 (1.1) 
East Central 1306 (19.9) 96 (1.5) 2128 (19.2) 225 (2.0) 
Kampala 1835 (13.6) 90 (0.7) 3533 (13.7) 235 (0.9) 
Mid-Eastern 752 (15.5) 60 (1.2) 1004 (17.4) 115 (2.0) 
Mid-Northern 2445 (19.2) 160 (1.3) 4067 (18.5) 394 (1.8) 
Mid-Western 1431 (11.1) 64 (0.5) 848 (14.5) 59 (1.0) 
North-Eastern 702 (15.8) 46 (1.0) 1100 (16.4) 100 (1.5) 
South-Western 631 (4.6) 23 (0.2) 135 (6.4) 3 (0.1) 
West Nile 415 (13.8) 14 (0.5) 422 (16.5) 19 (0.7) 
Total 12 979 (13.3) 716 (0.7) 17 380 (15.5) 1422 (1.3) 
Region of UgandaUS3 (1 year) (97 631 samples)Post-US3 (3 years) (112 352 samples)
SCT (%)SCD (%)SCT (%)SCD (%)
Central 1 1896 (12.9) 69 (0.5) 2497 (13.1) 144 (0.8) 
Central 2 1566 (14.1) 94 (0.8) 1646 (14.4) 128 (1.1) 
East Central 1306 (19.9) 96 (1.5) 2128 (19.2) 225 (2.0) 
Kampala 1835 (13.6) 90 (0.7) 3533 (13.7) 235 (0.9) 
Mid-Eastern 752 (15.5) 60 (1.2) 1004 (17.4) 115 (2.0) 
Mid-Northern 2445 (19.2) 160 (1.3) 4067 (18.5) 394 (1.8) 
Mid-Western 1431 (11.1) 64 (0.5) 848 (14.5) 59 (1.0) 
North-Eastern 702 (15.8) 46 (1.0) 1100 (16.4) 100 (1.5) 
South-Western 631 (4.6) 23 (0.2) 135 (6.4) 3 (0.1) 
West Nile 415 (13.8) 14 (0.5) 422 (16.5) 19 (0.7) 
Total 12 979 (13.3) 716 (0.7) 17 380 (15.5) 1422 (1.3) 

Samples were collected using targeted screening from the districts with the highest burden. Results confirm the high burden of SCT and SCD in Uganda, especially in the East Central and Mid-Northern regions.

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