Characteristics of adults with SCD and DM enrolled in Medicaid for at least 365 days
| Characteristic . | All patients, N = 457 . | Metformin treatment . | Adherence to metformin (MPR)* . | |||
|---|---|---|---|---|---|---|
| No, n = 315 . | Yes, n = 142 . | MPR < 40%, n = 42 . | MPR ≥ 40% to < 80%, n = 49 . | MPR ≥ 80%, n = 37 . | ||
| Females, n (%) | 330 (72) | 224 (71) | 106 (75) | 29 (69) | 36 (73) | 29 (78) |
| Age, mean (SD), y | 42.5 (11.4) | 42.1 (11.2) | 43.5 (11.9) | 41.2 (12.0) | 45.1 (12.5) | 45.3 (10.6) |
| Age, median (IQR), y | 43 (33-52) | 42 (33-50) | 44 (32-53) | 43 (28-51) | 46 (35-53) | 51 (38-53) |
| Age groups, n (%) | ||||||
| 18-39 y | 184 (40) | 130 (41) | 54 (38) | 18 (43) | 16 (33) | 11 (30) |
| ≥40 y | 273 (60) | 185 (59) | 88 (62) | 24 (57) | 33 (67) | 26 (70) |
| Comorbidity score, mean (SD)† | 2.6 (3.3) | 2.9 (3.5) | 1.9 (2.6) | 2.6 (2.8) | 1.3 (2.2) | 1.9 (2.7) |
| Comorbidity score, median (IQR)† | 1 (0-4) | 1 (0-5) | 1 (0-3) | 2 (0-4) | 0 (0-1) | 1 (0-2) |
| Characteristic . | All patients, N = 457 . | Metformin treatment . | Adherence to metformin (MPR)* . | |||
|---|---|---|---|---|---|---|
| No, n = 315 . | Yes, n = 142 . | MPR < 40%, n = 42 . | MPR ≥ 40% to < 80%, n = 49 . | MPR ≥ 80%, n = 37 . | ||
| Females, n (%) | 330 (72) | 224 (71) | 106 (75) | 29 (69) | 36 (73) | 29 (78) |
| Age, mean (SD), y | 42.5 (11.4) | 42.1 (11.2) | 43.5 (11.9) | 41.2 (12.0) | 45.1 (12.5) | 45.3 (10.6) |
| Age, median (IQR), y | 43 (33-52) | 42 (33-50) | 44 (32-53) | 43 (28-51) | 46 (35-53) | 51 (38-53) |
| Age groups, n (%) | ||||||
| 18-39 y | 184 (40) | 130 (41) | 54 (38) | 18 (43) | 16 (33) | 11 (30) |
| ≥40 y | 273 (60) | 185 (59) | 88 (62) | 24 (57) | 33 (67) | 26 (70) |
| Comorbidity score, mean (SD)† | 2.6 (3.3) | 2.9 (3.5) | 1.9 (2.6) | 2.6 (2.8) | 1.3 (2.2) | 1.9 (2.7) |
| Comorbidity score, median (IQR)† | 1 (0-4) | 1 (0-5) | 1 (0-3) | 2 (0-4) | 0 (0-1) | 1 (0-2) |
IQR, interquartile range; SD, standard deviation.
MPR calculated by dividing the sum of days supply of metformin by the number of days enrolled, minus the days hospitalized.
Charlson Comorbidity Index score is calculated as a sum of 19 categories of comorbidity and predicts the 10-year mortality for a patient who may have a range of comorbid conditions.