Table 1

Sequences of peptides identified by in-gel digestion of thrombin-generated C5-derived fragments

Fragment size, kDaNo. of sequences identifiedMost N-terminal sequenceMost C-terminal sequencePosition in C5 sequence*
11 kieeiaak  682-689 
   afteccvvasqlr 727-739 
24 10 tllpvskpeirs  756-766 
   esysgvtldpr 937-947 
35 11 kieeiaak  682-689 
   esysgvtldpr 937-947 
80 16 ipldlvpk  963-970 
   vtctnaelvk 1604-1613 
Fragment size, kDaNo. of sequences identifiedMost N-terminal sequenceMost C-terminal sequencePosition in C5 sequence*
11 kieeiaak  682-689 
   afteccvvasqlr 727-739 
24 10 tllpvskpeirs  756-766 
   esysgvtldpr 937-947 
35 11 kieeiaak  682-689 
   esysgvtldpr 937-947 
80 16 ipldlvpk  963-970 
   vtctnaelvk 1604-1613 
*

Positions identified by comparison with the sequence of human C5 (NCBI accession number P01031.4).

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