Multivariate analysis of factors influencing OS in the subgroup of patients receiving transplantation after RIC
Variable . | No. . | HR . | 95% CI . | P . |
---|---|---|---|---|
Age range at transplantation, y | ||||
15-55 | 122 | 1.000 | Reference | |
56-72 | 178 | 1.127 | (0.834-1.523) | .435 |
Sex | ||||
Female | 147 | 1.000 | Reference | |
Male | 153 | 1.475 | (1.100-1.978) | .009 |
Disease status at transplantation | ||||
CR | 110 | 1.000 | Reference | |
Non-CR | 176 | 1.743 | (1.249-2.432) | .001 |
Unknown | 14 | 1.959 | (0.998-3.843) | .051 |
PS | ||||
0 | 117 | 1.000 | Reference | |
1 | 140 | 1.803 | (1.293-2.516) | < .001 |
2-4 | 38 | 6.175 | (3.908-9.756) | < .001 |
Unknown | 5 | 4.979 | (1.849-13.409) | .001 |
Relationship between recipient and donor | ||||
HLA-matched related | 114 | 1.000 | Reference | |
HLA-mismatched related | 41 | 1.279 | (0.836-1.959) | .257 |
Unrelated | 145 | 1.237 | (0.895-1.710) | .198 |
Type of RIC | ||||
Flu + BU-based | 165 | 1.000 | Reference | |
Flu + Mel-based | 86 | 0.645 | (0.453-0.918) | .015 |
Others | 49 | 0.854 | (0.557-1.310) | .470 |
Variable . | No. . | HR . | 95% CI . | P . |
---|---|---|---|---|
Age range at transplantation, y | ||||
15-55 | 122 | 1.000 | Reference | |
56-72 | 178 | 1.127 | (0.834-1.523) | .435 |
Sex | ||||
Female | 147 | 1.000 | Reference | |
Male | 153 | 1.475 | (1.100-1.978) | .009 |
Disease status at transplantation | ||||
CR | 110 | 1.000 | Reference | |
Non-CR | 176 | 1.743 | (1.249-2.432) | .001 |
Unknown | 14 | 1.959 | (0.998-3.843) | .051 |
PS | ||||
0 | 117 | 1.000 | Reference | |
1 | 140 | 1.803 | (1.293-2.516) | < .001 |
2-4 | 38 | 6.175 | (3.908-9.756) | < .001 |
Unknown | 5 | 4.979 | (1.849-13.409) | .001 |
Relationship between recipient and donor | ||||
HLA-matched related | 114 | 1.000 | Reference | |
HLA-mismatched related | 41 | 1.279 | (0.836-1.959) | .257 |
Unrelated | 145 | 1.237 | (0.895-1.710) | .198 |
Type of RIC | ||||
Flu + BU-based | 165 | 1.000 | Reference | |
Flu + Mel-based | 86 | 0.645 | (0.453-0.918) | .015 |
Others | 49 | 0.854 | (0.557-1.310) | .470 |