Time trends in HCT for myelofibrosis: data from CIBMTR
Characteristics of patients . | 1997-2000, N (%) . | 2001-2004, N (%) . | 2005-2008, N (%) . |
---|---|---|---|
No. of patients | 72 | 213 | 336 |
No. of centers | 47 | 114 | 123 |
Age, y | |||
≤ 9 | 1 (1) | 0 | 3 (1) |
10-19 | 1 (1) | 5 (2) | 8 (2) |
20-29 | 3 (4) | 3 (1) | 4 (1) |
30-39 | 12 (17) | 20 (9) | 11 (3) |
40-49 | 26 (36) | 76 (36) | 69 (21) |
50-59 | 25 (35) | 82 (38) | 151 (45) |
60-69 | 4 (6) | 25 (12) | 87 (26) |
≥ 70 | 0 | 2 (1) | 3 (1) |
Donor group | |||
HLA-identical sibling | 36 (50) | 111 (52) | 142 (42) |
Other related | 3 (4) | 9 (4) | 12 (4) |
Unrelated | 33 (46) | 93 (44) | 182 (54) |
Graft type | |||
BM | 48 (67) | 45 (21) | 48 (14) |
PBSCs | 24 (33) | 168 (79) | 284 (85) |
CB | 0 | 0 | 4 (1) |
Conditioning regimen | |||
Proportion of RIC | 15% | 37% | 45% |
Characteristics of patients . | 1997-2000, N (%) . | 2001-2004, N (%) . | 2005-2008, N (%) . |
---|---|---|---|
No. of patients | 72 | 213 | 336 |
No. of centers | 47 | 114 | 123 |
Age, y | |||
≤ 9 | 1 (1) | 0 | 3 (1) |
10-19 | 1 (1) | 5 (2) | 8 (2) |
20-29 | 3 (4) | 3 (1) | 4 (1) |
30-39 | 12 (17) | 20 (9) | 11 (3) |
40-49 | 26 (36) | 76 (36) | 69 (21) |
50-59 | 25 (35) | 82 (38) | 151 (45) |
60-69 | 4 (6) | 25 (12) | 87 (26) |
≥ 70 | 0 | 2 (1) | 3 (1) |
Donor group | |||
HLA-identical sibling | 36 (50) | 111 (52) | 142 (42) |
Other related | 3 (4) | 9 (4) | 12 (4) |
Unrelated | 33 (46) | 93 (44) | 182 (54) |
Graft type | |||
BM | 48 (67) | 45 (21) | 48 (14) |
PBSCs | 24 (33) | 168 (79) | 284 (85) |
CB | 0 | 0 | 4 (1) |
Conditioning regimen | |||
Proportion of RIC | 15% | 37% | 45% |
PBSCs indicates peripheral blood stem cells; CB, cord blood; and RIC, reduced intensity conditioning.