Table 4

Response rate in patients with high-risk cytogenetics: t(4;14), t(14;16), del 17p

QT + V, n = 23TD, n = 22VTD, n = 23
CR, % 22* 0* 35* 
VGPR, % 27 22 
PR, % 30 18 22 
SD, % 13 14 
PD, % 26 41 3 
Early deaths, % 
QT + V, n = 23TD, n = 22VTD, n = 23
CR, % 22* 0* 35* 
VGPR, % 27 22 
PR, % 30 18 22 
SD, % 13 14 
PD, % 26 41 3 
Early deaths, % 

QT + V indicates chemotherapy + bortezomib; TD, thalidomide/dexamethasone; VTD, bortezomib/thalidomide/dexamethasone; CR, complete response; VGPR, very good partial response; PR, partial response; SD, stable disease; and PD, progressive disease.

*

VTD vs TD, P = .002; VTD vs QT + V, P = .02.

VTD vs TD, P = .004; VTD vs QT + V, P = .04.

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