Response rate to induction therapy according to treatment arm
. | QT + V, n = 129 . | TD, n = 127 . | VTD, n = 130 . |
---|---|---|---|
CR, % | 21* | 14* | 35* |
VGPR, % | 15 | 15 | 25 |
PR, % | 39 | 33 | 25 |
SD, % | 12 | 12 | 6 |
PD, % | 12† | 23 | 7‡ |
Early deaths, % | 1 | 1 | 2 |
. | QT + V, n = 129 . | TD, n = 127 . | VTD, n = 130 . |
---|---|---|---|
CR, % | 21* | 14* | 35* |
VGPR, % | 15 | 15 | 25 |
PR, % | 39 | 33 | 25 |
SD, % | 12 | 12 | 6 |
PD, % | 12† | 23 | 7‡ |
Early deaths, % | 1 | 1 | 2 |
QT + V indicates chemotherapy + bortezomib; TD, thalidomide/dexamethasone; VTD, bortezomib/thalidomide/dexamethasone; CR, complete response; VGPR, very good partial response; PR, partial response; SD, stable disease; and PD, progressive disease.
VTD vs QT + V, P = .01; VTD vs TD, P = .0001.
QT + V vs TD, P = .02.
VTD vs TD, P = .0004.