Table 1 Clinical and biologic features... | American Society of Hematology

Table 1

Clinical and biologic features of CLL patients at diagnosis

No. patients	N = 106^a
Median age, y (range)	64 (32-84)
Female, no. (%)	41 (39)
Binet stage, no. (%)
A	89 (84)
B	12 (11)
C	5 (5)
Lymphocytes, no./μL^b,c	14 900 ± 1800
Lymphocytes, %^b,d	65.4 ± 1.5
Hb, g/dL^b,c	13.9 ± 0.2
Plts, no./μL^b,e	201000 ± 6000
LDH, U/mL^b,f	358 ± 11
β2M, g/dL^b,g	2.2 ± 0.1
% B CLL clone^b,h	72 ± 2
CD38+, no. (%)^b,i	37 (35)
ZAP70+, no. (%)^e,j	27 (26)
K-light chain, no. (%)^h	57 (57)
Cytogenetics^k
Normal karyotype, no. (%)	38 (38)
del (11)	10 (10)
del (13)	44 (44)
del (17)	13 (13)
IGHV unmutated, no. (%)^l	34 (35)

No. patients	N = 106^a
Median age, y (range)	64 (32-84)
Female, no. (%)	41 (39)
Binet stage, no. (%)
A	89 (84)
B	12 (11)
C	5 (5)
Lymphocytes, no./μL^b,c	14 900 ± 1800
Lymphocytes, %^b,d	65.4 ± 1.5
Hb, g/dL^b,c	13.9 ± 0.2
Plts, no./μL^b,e	201000 ± 6000
LDH, U/mL^b,f	358 ± 11
β2M, g/dL^b,g	2.2 ± 0.1
% B CLL clone^b,h	72 ± 2
CD38+, no. (%)^b,i	37 (35)
ZAP70+, no. (%)^e,j	27 (26)
K-light chain, no. (%)^h	57 (57)
Cytogenetics^k
Normal karyotype, no. (%)	38 (38)
del (11)	10 (10)
del (13)	44 (44)
del (17)	13 (13)
IGHV unmutated, no. (%)^l	34 (35)

CLL indicates chronic lymphocytic leukemia; IGHV, immunoglobulin heavy chain variable; LDH, lactate dehydrogenase; and Plts, platelets.

All cases were evaluable for each of the variables, if not otherwise specified.

Data are expressed as mean ± SEM.

Data were available in 105 patients.

Data were available in 103 patients.

Data were available in 104 patients.

Data were available in 93 patients.

Data were available in 53 patients.

Data were available in 100 patients.

CD38 expression was considered positive when > 30%.

ZAP70 expression was considered positive when > 20%.

Data were available in 101 patients.

Data were available in 97 patients.