Absolute and relative risks for VTE in relatives dependent on IT
| Type of IT . | Exposure time, y . | Event, n . | Annual incidence, % (95% CI) . | Hazard ratio,* % (95% CI) . | P . |
|---|---|---|---|---|---|
| AT/PC/PS | 463 | 13 | 2.82 (1.63-4.80) | 25.7 (12.2-54.2) | < .001 |
| FV G1691A | 2783 | 7 | 0.25 (0.12-0.53) | 1.7 (0.7-4.4) | .24 |
| FII G20210A | 1192 | 5 | 0.42 (0.17-1.01) | 2.6 (0.9-7.6) | .09 |
| Combined defects | 258 | 6 | 2.33 (1.04-5.19) | 19.6 (7.7-49.6) | < .01 |
| No IT | 13 567 | 14 | 0.10 (0.06-0.17) | 1 | 1 |
| Total | 18 278 | 47 | 0.26 (0.19-0.34) |
| Type of IT . | Exposure time, y . | Event, n . | Annual incidence, % (95% CI) . | Hazard ratio,* % (95% CI) . | P . |
|---|---|---|---|---|---|
| AT/PC/PS | 463 | 13 | 2.82 (1.63-4.80) | 25.7 (12.2-54.2) | < .001 |
| FV G1691A | 2783 | 7 | 0.25 (0.12-0.53) | 1.7 (0.7-4.4) | .24 |
| FII G20210A | 1192 | 5 | 0.42 (0.17-1.01) | 2.6 (0.9-7.6) | .09 |
| Combined defects | 258 | 6 | 2.33 (1.04-5.19) | 19.6 (7.7-49.6) | < .01 |
| No IT | 13 567 | 14 | 0.10 (0.06-0.17) | 1 | 1 |
| Total | 18 278 | 47 | 0.26 (0.19-0.34) |
IT indicates inherited thrombophilia; and VTE, venous thromboembolism.
Adjusted for age and sex.