Table 1 SNP frequency in MIPs and in the... | American Society of Hematology

Table 1

SNP frequency in MIPs and in the human exome

Dataset	Length, bp	Nonsynonymous SNPs		Synonymous SNPs		Total SNPs
Dataset	Length, bp	n	SNPs/bp*	n	SNPs/bp†	n	SNPs/bp‡
MIPs	59994	230	0.0038	216	0.0036	446	0.0074
Exome	35201356	150158	0.0043	115376	0.0033	265534	0.0075

Dataset	Length, bp	Nonsynonymous SNPs		Synonymous SNPs		Total SNPs
Dataset	Length, bp	n	SNPs/bp*	n	SNPs/bp†	n	SNPs/bp‡
MIPs	59994	230	0.0038	216	0.0036	446	0.0074
Exome	35201356	150158	0.0043	115376	0.0033	265534	0.0075

MIPs correspond to 2282 unique peptides eluted from B-LCLs. The human exome corresponds to 264 401 CDS's extracted from Ensembl (GRCh37.65). dbSNP (Build 135) was used to calculate SNP frequency (SNPs/bp). P values were calculated using the 2-tailed Fisher exact test comparing MIP-coding sequences with the exome not encoding MIPs.

P = .12.

†

P = .16.

‡

P = .50.

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