Multivariate analysis of the CTLA4-CT60 GG genotype for acute GVHD (grade 1-4 vs no GVHD) in the HLA-matched subgroup, confirming this genotype as an independent risk factor
| Variable . | Univariate . | Multivariate . | ||
|---|---|---|---|---|
| OR (95% CI) . | P . | OR (95% CI) . | P . | |
| Recipient age | 1.017 (0.99-1.04) | .146 | 1.020 (0.99-1.05) | .121 |
| Donor age | 0.995 (0.97-1.03) | .763 | 0.997 (0.97-1.03) | .854 |
| Female to male transplant | 1.644 (0.93-2.89) | .085 | 1.630 (0.89-2.97) | .111 |
| Diagnosis ANLL vs ALL | 1.280 (0.81-2.03) | .296 | 1.129 (0.69-1.85) | .631 |
| Total body irradiation | 0.847 (0.43-1.68) | .634 | 0.916 (0.45-1.86) | .809 |
| Relapse | 1.255 (0.77-2.06) | .369 | 1.330 (0.80-2.24) | .273 |
| Genotype GG | 0.468 (0.29-0.75) | .002 | 0.497 (0.31-0.80) | .004 |
| Variable . | Univariate . | Multivariate . | ||
|---|---|---|---|---|
| OR (95% CI) . | P . | OR (95% CI) . | P . | |
| Recipient age | 1.017 (0.99-1.04) | .146 | 1.020 (0.99-1.05) | .121 |
| Donor age | 0.995 (0.97-1.03) | .763 | 0.997 (0.97-1.03) | .854 |
| Female to male transplant | 1.644 (0.93-2.89) | .085 | 1.630 (0.89-2.97) | .111 |
| Diagnosis ANLL vs ALL | 1.280 (0.81-2.03) | .296 | 1.129 (0.69-1.85) | .631 |
| Total body irradiation | 0.847 (0.43-1.68) | .634 | 0.916 (0.45-1.86) | .809 |
| Relapse | 1.255 (0.77-2.06) | .369 | 1.330 (0.80-2.24) | .273 |
| Genotype GG | 0.468 (0.29-0.75) | .002 | 0.497 (0.31-0.80) | .004 |