Expression levels of coagulation factors in macLRP1+ and macLRP1− mice
| . | Factor IX, U/mL . | Factor X, U/mL . | Factor VIII, U/mL . | VWF, U/mL . |
|---|---|---|---|---|
| macLRP1+ | 1.1 ± 0.1 | 0.9 ± 0.1 | 1.0 ± 0.3 | 1.0 ± 0.4 |
| macLRP1− | 1.2 ± 0.3 | 1.0 ± 0.1 | 1.3 ± 0.3 | 1.6 ± 0.4 |
| P | .17 | .31 | < .0001 | < .0001 |
| . | Factor IX, U/mL . | Factor X, U/mL . | Factor VIII, U/mL . | VWF, U/mL . |
|---|---|---|---|---|
| macLRP1+ | 1.1 ± 0.1 | 0.9 ± 0.1 | 1.0 ± 0.3 | 1.0 ± 0.4 |
| macLRP1− | 1.2 ± 0.3 | 1.0 ± 0.1 | 1.3 ± 0.3 | 1.6 ± 0.4 |
| P | .17 | .31 | < .0001 | < .0001 |
Data represent mean ± SD. Factor IX and factor X levels were determined in 10 and 12 macLRP1+ and macLRP1− mice, respectively. FVIII and VWF levels were determined in 42 and 39 macLRP1+ and macLRP1− mice, respectively.