Patients' demographic and clinical characteristics
Variable . | FCR . | 90YFC . | P . |
---|---|---|---|
No. of patients | 47 | 26 | |
Median age, y (range) | 53 (33-68) | 55 (29-66) | .3 |
Sex, no. (%) | |||
Male | 25 (53) | 16 (61) | .3 |
Female | 22 (47) | 10 (38) | |
Lactate dehydrogenase > normal, no. (%) | 12 (25) | 5 (20) | .4 |
Median β2-microglobulin, Mg/L (range) | 2 (1.2-6.5) | 2 (0.6-3.3) | .2 |
PET+, no./total (%) | 7 (15) | 11/25 (44) | .01 |
111Ibrituximab-positive scan, no./total (%) | 0 | 10/25 (40) | |
No. of prior chemotherapies, median (range) | 3 (2-7) | 3 (2-7) | .7 |
Prior autologous transplantation, no. (%) | 9 (19) | 0 | |
Grade, no. (%) | .6 | ||
1 or 2 | 37 (79) | 21 (81) | |
3 | 10 (21) | 3 (12) | |
Nonspecified | 0 | 2 (7) | |
Median time from diagnosis to transplantation, y (range) | 3 (0.7-24) | 2 (1.1-13.1) | .2 |
Disease status at transplantation, no. (%) | < .001 | ||
CR | 18 (38) | 8 (31) | |
Partial remission | 29 (52) | 8 (31) | |
Chemorefractory | 0 | 10 (38) | |
Stem cell source, no. (%) | < .001 | ||
Matched related | 45 (96) | 15 (58) | |
Matched unrelated | 2 (4) | 8 (31) | |
Mismatched related | 0 | 1 (4) | |
Mismatched unrelated | 0 | 2 (8) |
Variable . | FCR . | 90YFC . | P . |
---|---|---|---|
No. of patients | 47 | 26 | |
Median age, y (range) | 53 (33-68) | 55 (29-66) | .3 |
Sex, no. (%) | |||
Male | 25 (53) | 16 (61) | .3 |
Female | 22 (47) | 10 (38) | |
Lactate dehydrogenase > normal, no. (%) | 12 (25) | 5 (20) | .4 |
Median β2-microglobulin, Mg/L (range) | 2 (1.2-6.5) | 2 (0.6-3.3) | .2 |
PET+, no./total (%) | 7 (15) | 11/25 (44) | .01 |
111Ibrituximab-positive scan, no./total (%) | 0 | 10/25 (40) | |
No. of prior chemotherapies, median (range) | 3 (2-7) | 3 (2-7) | .7 |
Prior autologous transplantation, no. (%) | 9 (19) | 0 | |
Grade, no. (%) | .6 | ||
1 or 2 | 37 (79) | 21 (81) | |
3 | 10 (21) | 3 (12) | |
Nonspecified | 0 | 2 (7) | |
Median time from diagnosis to transplantation, y (range) | 3 (0.7-24) | 2 (1.1-13.1) | .2 |
Disease status at transplantation, no. (%) | < .001 | ||
CR | 18 (38) | 8 (31) | |
Partial remission | 29 (52) | 8 (31) | |
Chemorefractory | 0 | 10 (38) | |
Stem cell source, no. (%) | < .001 | ||
Matched related | 45 (96) | 15 (58) | |
Matched unrelated | 2 (4) | 8 (31) | |
Mismatched related | 0 | 1 (4) | |
Mismatched unrelated | 0 | 2 (8) |