Combined GEP 70-gene and sIL6r-risk groups annotated with 1q21 vCA, rs2228145 genotype, and sIL-6r concentration (N = 626)
| . | Low-risk GEP/low sIL-6r (n = 451) . | Low-risk GEP/high sIL-6r (n = 94) . | High-risk GEP/low sIL-r (n = 46) . | High-risk GEP/high sIL-6r (n = 35) . |
|---|---|---|---|---|
| % with 1q21 Amp | 26.8 | 59.6 | 58.7 | 94.3 |
| Average sIL-6r, ng/mL | 48.3 | 115.8 | 51.6 | 142.5 |
| % AA | 39.7 | 10.6 | 45.7 | 28.6 |
| % of AA with Amp | 31.2 | 70.0 | 85.7 | 100 |
| AA NL average sIL-6r, ng/mL | 37.2 | 106.4 | 32.2 | NA |
| AA Amp average sIL-6r, ng/mL | 43.7 | 102.5 | 50.4 | 122.1 |
| % AC | 47.7 | 51.1 | 47.8 | 40.0 |
| % of AC with Amp | 25.1 | 62.5 | 36.4 | 85.7 |
| AC NL average sIL-6r, ng/mL | 50.7 | 116.1 | 53.9 | 97.8 |
| AC Amp average sIL-6r, ng/mL | 55.6 | 119.3 | 54.2 | 144.9 |
| % CC | 12.6 | 38.3 | 6.5 | 31.4 |
| % of CC with Amp | 19.3 | 52.8 | 33.3 | 100 |
| CC NL average sIL-6r, ng/mL | 62.5 | 102.7 | 63.5 | NA |
| CC Amp average sIL-6r, ng/mL | 64.8 | 128.6 | 51.7 | 166.6 |
| . | Low-risk GEP/low sIL-6r (n = 451) . | Low-risk GEP/high sIL-6r (n = 94) . | High-risk GEP/low sIL-r (n = 46) . | High-risk GEP/high sIL-6r (n = 35) . |
|---|---|---|---|---|
| % with 1q21 Amp | 26.8 | 59.6 | 58.7 | 94.3 |
| Average sIL-6r, ng/mL | 48.3 | 115.8 | 51.6 | 142.5 |
| % AA | 39.7 | 10.6 | 45.7 | 28.6 |
| % of AA with Amp | 31.2 | 70.0 | 85.7 | 100 |
| AA NL average sIL-6r, ng/mL | 37.2 | 106.4 | 32.2 | NA |
| AA Amp average sIL-6r, ng/mL | 43.7 | 102.5 | 50.4 | 122.1 |
| % AC | 47.7 | 51.1 | 47.8 | 40.0 |
| % of AC with Amp | 25.1 | 62.5 | 36.4 | 85.7 |
| AC NL average sIL-6r, ng/mL | 50.7 | 116.1 | 53.9 | 97.8 |
| AC Amp average sIL-6r, ng/mL | 55.6 | 119.3 | 54.2 | 144.9 |
| % CC | 12.6 | 38.3 | 6.5 | 31.4 |
| % of CC with Amp | 19.3 | 52.8 | 33.3 | 100 |
| CC NL average sIL-6r, ng/mL | 62.5 | 102.7 | 63.5 | NA |
| CC Amp average sIL-6r, ng/mL | 64.8 | 128.6 | 51.7 | 166.6 |
NA indicates not applicable.